Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASR | P41180 | 11/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 4/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | CRHBP | P24387 | 1/20 | 0.32 |
| ▸ | GALK1 | P51570 | 1/20 | 0.32 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30892234 | 1.00 | CASR (0.40) | CASRALDH1A1POLBMAPTKMT2A | |
| SCHEMBL29281783 | 0.88 | CASR (0.43) | CASRMAPTSMN1; SMN2HTT | |
| SCHEMBL30892233 | 0.88 | CASR (0.43) | CASRMAPTSMN1; SMN2HTT | |
| SCHEMBL29281784 | 0.87 | CASR (0.42) | CASRALDH1A1MAPTKMT2AMEN1 | |
| SCHEMBL29281787 | 0.87 | CASR (0.42) | CASRALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL30892238 | 0.87 | CASR (0.42) | CASRALDH1A1MAPTKMT2AMEN1 | |
| SCHEMBL30892239 | 0.87 | CASR (0.42) | CASRALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL30892237 | 0.84 | CASR (0.57) | CASRALDH1A1POLBHTTRECQL | |
| SCHEMBL29281794 | 0.84 | CASR (0.57) | CASRALDH1A1POLBHTTRECQL | |
| SCHEMBL30892242 | 0.81 | CASR (0.44) | CASRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117945824-A | Deuterated methyl enaminone compound and preparation method thereof | 南京工业大学 | 2024-04-30 | — | — | CN | disclosed |