SCHEMBL29282116

SCHEMBL29282116

Cc1cc(C(C)(C)C)c(O)c(C)c1CCl.[NaH]

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2C19 P33261 6/20 0.50
CYP1A2 P05177 5/20 0.50
LMNA P02545 4/20 0.50
CYP3A4 P08684 4/20 0.50
TSHR P16473 4/20 0.50
CYP2D6 P10635 3/20 0.50
MEN1 O00255 3/20 0.50
KMT2A Q03164 3/20 0.50
HTR1A P08908 2/20 0.50
ADRA2A P08913 2/20 0.50
PTGS2 P35354 2/20 0.50
CHRM2 P08172 1/20 0.50
CHRM4 P08173 1/20 0.50
CHRM5 P08912 1/20 0.50
CHRM1 P11229 1/20 0.50
ADRA2B P18089 1/20 0.50
ADRA2C P18825 1/20 0.50
ADRA1D P25100 1/20 0.50
HTR1D P28221 1/20 0.50
HTR1B P28222 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29824041 0.98 CYP2C19 (0.51) CYP2C19CYP1A2LMNACYP3A4TSHR
SCHEMBL1720100 0.98 CYP2C19 (0.51) CYP2C19CYP1A2LMNACYP3A4TSHR
SCHEMBL30913182 0.96 CYP2C19 (0.50) CYP2C19CYP1A2LMNACYP3A4TSHR
SCHEMBL9352680 0.85 CYP2C19 (0.51) CYP2C19CYP1A2LMNACYP3A4TSHR
SCHEMBL9348782 0.84 CYP2C19 (0.46) CYP2C19CYP1A2LMNACYP3A4TSHR
SCHEMBL10814873 0.83 CYP2C19 (0.61) CYP2C19CYP1A2LMNACYP3A4TSHR
SCHEMBL9349122 0.82 CYP2C19 (0.45) CYP2C19CYP1A2LMNACYP3A4TSHR
SCHEMBL30913172 0.81 CYP2C19 (0.52) CYP2C19CYP1A2LMNACYP3A4TSHR
SCHEMBL30913173 0.81 CYP2C19 (0.52) CYP2C19CYP1A2LMNACYP3A4TSHR
SCHEMBL10000643 0.81 CYP2C19 (0.52) CYP2C19CYP1A2LMNACYP3A4TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117986196-A Clean preparation method of antioxidant 1790 巨野百林化学有限公司 2024-05-07 CN disclosed