Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNT1 | O60563 | 20/20 | 0.78 |
| ▸ | CCNK | O75909 | 20/20 | 0.78 |
| ▸ | CDK9 | P50750 | 20/20 | 0.78 |
| ▸ | CDK12 | Q9NYV4 | 20/20 | 0.78 |
| ▸ | CCNE1 | P24864 | 18/20 | 0.78 |
| ▸ | CDK2 | P24941 | 18/20 | 0.78 |
| ▸ | CDK7 | P50613 | 5/20 | 0.78 |
| ▸ | CCNH | P51946 | 5/20 | 0.78 |
| ▸ | MNAT1 | P51948 | 3/20 | 0.78 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29283736 | 1.00 | CCNT1 (0.78) | CCNT1CCNKCDK9CDK12CCNE1 | |
| SCHEMBL29749340 | 1.00 | CCNT1 (0.78) | CCNT1CCNKCDK9CDK12CCNE1 | |
| SCHEMBL25327879 | 0.94 | CCNT1 (0.69) | CCNT1CCNKCDK9CDK12CCNE1 | |
| SCHEMBL25327884 | 0.94 | CCNT1 (0.69) | CCNT1CCNKCDK9CDK12CCNE1 | |
| SCHEMBL30524024 | 0.94 | CCNT1 (0.69) | CCNT1CCNKCDK9CDK12CCNE1 | |
| SCHEMBL31666586 | 0.89 | CCNT1 (0.76) | CCNT1CCNKCDK9CDK12CCNE1 | |
| SCHEMBL31666762 | 0.89 | CCNT1 (0.76) | CCNT1CCNKCDK9CDK12CCNE1 | |
| SCHEMBL24839343 | 0.88 | CCNK (1.00) | CCNT1CCNKCDK9CDK12CCNE1 | |
| SCHEMBL29498427 | 0.88 | CCNK (1.00) | CCNT1CCNKCDK9CDK12CCNE1 | |
| SCHEMBL31666555 | 0.87 | CCNK (0.81) | CCNT1CCNKCDK9CDK12CCNE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118176189-A | Pyrimidine derivative, preparation method and application thereof | 成都苑东生物制药股份有限公司 | 2024-06-11 | — | — | CN | disclosed |