Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.49 |
| ▸ | CDK7 | P50613 | 8/20 | 0.47 |
| ▸ | CCNH | P51946 | 8/20 | 0.47 |
| ▸ | MNAT1 | P51948 | 8/20 | 0.47 |
| ▸ | MAPK3 | P27361 | 6/20 | 0.45 |
| ▸ | CCNK | O75909 | 6/20 | 0.45 |
| ▸ | CDK2 | P24941 | 5/20 | 0.45 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.45 |
| ▸ | CDK13 | Q14004 | 1/20 | 0.45 |
| ▸ | CDK12 | Q9NYV4 | 5/20 | 0.44 |
| ▸ | CCNT1 | O60563 | 4/20 | 0.44 |
| ▸ | CDK9 | P50750 | 4/20 | 0.44 |
| ▸ | CCNE1 | P24864 | 4/20 | 0.44 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.44 |
| ▸ | CDK1 | P06493 | 1/20 | 0.44 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.44 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29283742 | 1.00 | TRPV1 (0.49) | TRPV1CDK7CCNHMNAT1MAPK3 | |
| SCHEMBL29283727 | 0.90 | CDK7 (0.46) | TRPV1CDK7CCNHMNAT1MAPK3 | |
| SCHEMBL29283724 | 0.90 | CDK7 (0.46) | TRPV1CDK7CCNHMNAT1MAPK3 | |
| SCHEMBL29283744 | 0.89 | CDK7 (0.45) | TRPV1CDK7CCNHMNAT1MAPK3 | |
| SCHEMBL29283728 | 0.89 | CDK7 (0.45) | TRPV1CDK7CCNHMNAT1MAPK3 | |
| SCHEMBL29283725 | 0.89 | CDK7 (0.45) | TRPV1CDK7CCNHMNAT1MAPK3 | |
| SCHEMBL29283745 | 0.89 | CDK7 (0.45) | TRPV1CDK7CCNHMNAT1MAPK3 | |
| SCHEMBL21188533 | 0.87 | CDK2 (0.53) | TRPV1CDK7CCNHMNAT1CCNK | |
| SCHEMBL29749300 | 0.87 | CDK2 (0.53) | TRPV1CDK7CCNHMNAT1CCNK | |
| SCHEMBL29083554 | 0.87 | CDK2 (0.53) | TRPV1CDK7CCNHMNAT1CCNK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118176189-A | Pyrimidine derivative, preparation method and application thereof | 成都苑东生物制药股份有限公司 | 2024-06-11 | — | — | CN | disclosed |