Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM2 | Q14416 | 5/20 | 0.73 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.64 |
| ▸ | DHPS | P49366 | 1/20 | 0.50 |
| ▸ | HTR1D | P28221 | 1/20 | 0.45 |
| ▸ | CYP11B1 | P15538 | 4/20 | 0.44 |
| ▸ | CYP11B2 | P19099 | 4/20 | 0.44 |
| ▸ | BACE1 | P56817 | 1/20 | 0.44 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.44 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.44 |
| ▸ | ERN1 | O75460 | 1/20 | 0.42 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.42 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.41 |
| ▸ | METAP2 | P50579 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31006551 | 1.00 | GRM2 (0.73) | GRM2HSP90AB1DHPSHTR1DCYP11B1 | |
| SCHEMBL31006541 | 0.88 | GRM2 (0.69) | GRM2HSP90AB1DHPSHTR1DCYP11B1 | |
| SCHEMBL29283804 | 0.88 | GRM2 (0.69) | GRM2HSP90AB1DHPSHTR1DCYP11B1 | |
| SCHEMBL29283806 | 0.88 | HSP90AB1 (0.76) | GRM2HSP90AB1BACE1METAP2 | |
| SCHEMBL31006527 | 0.88 | HSP90AB1 (0.76) | GRM2HSP90AB1BACE1METAP2 | |
| SCHEMBL29283830 | 0.87 | HSP90AB1 (0.68) | GRM2HSP90AB1CYP11B1CYP11B2KDM4C | |
| SCHEMBL31006559 | 0.87 | HSP90AB1 (0.68) | GRM2HSP90AB1CYP11B1CYP11B2KDM4C | |
| SCHEMBL31006547 | 0.81 | HSP90AB1 (0.67) | GRM2HSP90AB1METAP2 | |
| SCHEMBL31006508 | 0.81 | HSP90AB1 (0.67) | GRM2HSP90AB1METAP2MAPT | |
| SCHEMBL29283810 | 0.81 | HSP90AB1 (0.67) | GRM2HSP90AB1METAP2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118184635-A | Quinolinone compound, pharmaceutical composition and application thereof | 安徽医科大学 | 2024-06-14 | — | — | CN | disclosed |