Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.65 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.45 |
| ▸ | HRH3 | Q9Y5N1 | 5/20 | 0.43 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | MMP13 | P45452 | 1/20 | 0.39 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.38 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31006553 | 1.00 | HSP90AB1 (0.65) | HSP90AB1GRM2HRH3ADORA2AHPGD | |
| SCHEMBL29283858 | 0.91 | HSP90AB1 (0.63) | HSP90AB1GRM2ADORA2AALDH1A1TSHR | |
| SCHEMBL31006546 | 0.91 | HSP90AB1 (0.63) | HSP90AB1GRM2ADORA2AALDH1A1TSHR | |
| SCHEMBL31006527 | 0.89 | HSP90AB1 (0.76) | HSP90AB1GRM2HDAC6METAP2 | |
| SCHEMBL29283806 | 0.89 | HSP90AB1 (0.76) | HSP90AB1GRM2HDAC6METAP2 | |
| SCHEMBL29283805 | 0.88 | HSP90AB1 (0.50) | HSP90AB1GRM2ADORA2AHPGDKDM4E | |
| SCHEMBL31006532 | 0.88 | HSP90AB1 (0.50) | HSP90AB1GRM2ADORA2AHPGDKDM4E | |
| SCHEMBL29283865 | 0.84 | HSP90AB1 (0.69) | HSP90AB1GRM2ALDH1A1GLATSHR | |
| SCHEMBL29283811 | 0.84 | HSP90AB1 (0.69) | HSP90AB1GRM2KDM4EALDH1A1MEN1 | |
| SCHEMBL31006557 | 0.84 | HSP90AB1 (0.60) | HSP90AB1GRM2ADORA2AKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118184635-A | Quinolinone compound, pharmaceutical composition and application thereof | 安徽医科大学 | 2024-06-14 | — | — | CN | disclosed |