Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23070949 | 0.92 | BRAF (0.53) | BRAFKCNH2 | |
| SCHEMBL3755095 | 0.85 | BRAF (0.56) | BRAFKCNH2 | |
| SCHEMBL2931218 | 0.83 | BRAF (0.57) | BRAFKCNH2 | |
| SCHEMBL2927751 | 0.83 | BRAF (0.57) | BRAF | |
| SCHEMBL2928625 | 0.82 | BRAF (0.59) | BRAF | |
| SCHEMBL15925248 | 0.81 | BRAF (0.57) | BRAFKCNH2 | |
| SCHEMBL22919873 | 0.81 | BRAF (0.57) | BRAFKCNH2 | |
| SCHEMBL16740695 | 0.81 | BRAF (0.70) | BRAFKCNH2 | |
| Hydrochloric Acid SCHEMBL29395876 | 0.80 | BRAF (0.56) | BRAFKCNH2 | |
| SCHEMBL15925259 | 0.80 | BRAF (0.69) | BRAFKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2229391-A1 | PYRIDO[2,3-B]PYRAZINE-8-SUBSTITUTED COMPOUNDS AND THEIR USE | Cancer Research Technology Limited (GB) | 2010-09-22 | — | — | EP | disclosed |
| WO-2009077766-A1 | PYRIDO[2,3-B]PYRAZINE-8-SUBSTITUTED COMPOUNDS AND THEIR USE | CANCER RESEARCH TECHNOLOGY LIMITED (GB) | 2009-06-25 | — | — | WO | disclosed |