Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 2/20 | 0.64 |
| ▸ | KDM1A | O60341 | 1/20 | 0.51 |
| ▸ | MAOB | P27338 | 1/20 | 0.51 |
| ▸ | CTSK | P43235 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.45 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.45 |
| ▸ | RELA | Q04206 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.43 |
| ▸ | DRD2 | P14416 | 2/20 | 0.42 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
| ▸ | JAK1 | P23458 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4204065 | 1.00 | BTK (0.64) | BTKKDM1AMAOBCTSKKMT2A | |
| SCHEMBL2722658 | 1.00 | BTK (0.64) | BTKKDM1AMAOBCTSKKMT2A | |
| SCHEMBL3766173 | 1.00 | BTK (0.64) | BTKKDM1AMAOBCTSKKMT2A | |
| SCHEMBL22998960 | 0.93 | BTK (0.58) | BTKKDM1AMAOBCTSKKMT2A | |
| SCHEMBL3708594 | 0.93 | BTK (0.58) | BTKKDM1AMAOBCTSKKMT2A | |
| SCHEMBL3708596 | 0.93 | BTK (0.58) | BTKKDM1AMAOBCTSKKMT2A | |
| SCHEMBL22084011 | 0.86 | BTK (0.59) | BTKKDM1AMAOBCTSKKMT2A | |
| SCHEMBL22084628 | 0.86 | BTK (0.59) | BTKKDM1AMAOBCTSKKMT2A | |
| SCHEMBL26180602 | 0.86 | BTK (0.59) | BTKKDM1AMAOBCTSKKMT2A | |
| SCHEMBL23912295 | 0.86 | BTK (0.59) | BTKKDM1AMAOBCTSKKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118265711-A | Chromanamidine monocyclic lactam antibiotics | 默沙东有限责任公司 | 2024-06-28 | — | — | CN | disclosed |