SCHEMBL29286497

SCHEMBL29286497

FC(F)(F)C1CNCCCO1

nearest known ligand 0.31

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
SLC6A2 P23975 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21969678 1.00 SLC6A2 (0.31) SLC6A2
Bromide SCHEMBL21905805 0.98 SLC6A2 (0.30) SLC6A2
Bromide SCHEMBL21905807 0.98 SLC6A2 (0.30) SLC6A2
SCHEMBL17340694 0.86 SLC6A2 (0.39) SLC6A2
SCHEMBL17340716 0.86 SLC6A2 (0.39) SLC6A2
SCHEMBL12275915 0.86 SLC6A2 (0.39) SLC6A2
Hydrochloric Acid SCHEMBL12482568 0.84 SLC6A2 (0.38) SLC6A2
Hydrochloric Acid SCHEMBL14919370 0.84 SLC6A2 (0.38) SLC6A2
Hydrochloric Acid SCHEMBL12482599 0.84 SLC6A2 (0.38) SLC6A2
SCHEMBL25146515 0.78 SLC6A2 (0.31) SLC6A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113272293-A 2-amino-N-heteroaryl-nicotinamide as NAV1.8 inhibitors 默沙东公司 2021-08-17 CN disclosed