Methacrylic Acid

Methacrylic Acid

SCHEMBL29289366

C=C(C)C(=O)O.CCCCNCCCC

nearest known ligand 0.50

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX15 P16050 1/20 0.50
PAOX Q6QHF9 1/20 0.47
TSHR P16473 4/20 0.46
ALDH1A1 P00352 2/20 0.46
CYP1A2 P05177 1/20 0.41
CYP3A4 P08684 1/20 0.41
CYP2D6 P10635 1/20 0.41
CYP2C19 P33261 1/20 0.41
EPHX1 P07099 2/20 0.40
GAA P10253 2/20 0.40
KDM4E B2RXH2 3/20 0.40
S1PR2 O95136 5/20 0.39
S1PR4 O95977 5/20 0.39
S1PR1 P21453 5/20 0.39
S1PR3 Q99500 5/20 0.39
S1PR5 Q9H228 1/20 0.39
ADH1B P00325 1/20 0.39
ADH1C P00326 1/20 0.39
ADH1A P07327 1/20 0.39
ADH7 P40394 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Methacrylic Acid SCHEMBL27472270 0.86 PAOX (0.50) ALOX15PAOXTSHRALDH1A1EPHX1
Acetic Acid SCHEMBL886850 0.85 TSHR (0.55) ALOX15PAOXTSHRALDH1A1CYP2C19
Methacrylic Acid SCHEMBL31299771 0.84 TSHR (0.57) ALOX15TSHRALDH1A1CYP1A2CYP3A4
Bicarbonate SCHEMBL5973584 0.83 TSHR (0.52) ALOX15PAOXTSHRALDH1A1CYP2C19
Bicarbonate SCHEMBL28699185 0.83 TSHR (0.58) ALOX15PAOXTSHRALDH1A1CYP2C19
Methacrylic Acid SCHEMBL4642347 0.83 TSHR (0.52) ALOX15TSHRALDH1A1MEN1KMT2A
Methacrylic Acid SCHEMBL2951797 0.83 TSHR (0.46) ALOX15TSHRALDH1A1MEN1KMT2A
Bicarbonate SCHEMBL910039 0.83 TSHR (0.58) ALOX15PAOXTSHRALDH1A1CYP2C19
Methacrylic Acid SCHEMBL9056338 0.83 TSHR (0.46) ALOX15TSHRALDH1A1MEN1KMT2A
Methacrylic Acid SCHEMBL3646864 0.83 TSHR (0.46) ALOX15TSHRALDH1A1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109486327-A The composition and its metal anti-corrosive paint of cation-type water-thinned Hydroxylated acrylic resin dispersion and siloxanes hydrolysate 上海大学 2019-03-19 CN disclosed