SCHEMBL2929003

SCHEMBL2929003

Cc1c(Nc2c(C#N)cncc2C=Cc2ccccc2)ccc2[nH]ccc12

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
PRKCQ Q04759 20/20 1.00
PRKCD Q05655 20/20 1.00

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2929281 1.00 PRKCQ (1.00) PRKCQPRKCD
SCHEMBL2929001 1.00 PRKCQ (1.00) PRKCQPRKCD
SCHEMBL2933884 0.94 PRKCQ (0.89) PRKCQPRKCD
SCHEMBL2933885 0.94 PRKCQ (0.89) PRKCQPRKCD
SCHEMBL2935427 0.92 PRKCQ (0.85) PRKCQPRKCD
SCHEMBL2933955 0.92 PRKCQ (0.85) PRKCQPRKCD
SCHEMBL2926764 0.92 PRKCQ (0.85) PRKCQPRKCD
SCHEMBL2935424 0.92 PRKCQ (0.85) PRKCQPRKCD
SCHEMBL2929569 0.91 PRKCQ (0.84) PRKCQPRKCD
SCHEMBL2927067 0.90 PRKCQ (0.82) PRKCQPRKCD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2229377-A1 5-ALKYL/ALKENYL-3-CYANOPYRIDINES AS KINASE INHIBITORS Wyeth LLC (US) 2010-09-22 EP claimed
WO-2009076602-A1 5-ALKYL/ALKENYL-3-CYANOPYRIDINES AS KINASE INHIBITORS WYETH (US) 2009-06-18 WO claimed
EP-2229377-A1 5-ALKYL/ALKENYL-3-CYANOPYRIDINES AS KINASE INHIBITORS Wyeth LLC (US) 2010-09-22 EP disclosed
WO-2009076602-A1 5-ALKYL/ALKENYL-3-CYANOPYRIDINES AS KINASE INHIBITORS WYETH (US) 2009-06-18 WO disclosed