Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RY14 | Q15391 | 1/20 | 0.57 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.41 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.40 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.39 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.38 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2934240 | 0.89 | P2RY14 (0.65) | P2RY14ALOX5MRGPRX4NR1H4LTB4R | |
| SCHEMBL2927190 | 0.88 | P2RY14 (0.64) | P2RY14ALOX5MRGPRX4LTB4RLTB4R2 | |
| SCHEMBL2932632 | 0.86 | P2RY14 (0.64) | P2RY14ALOX5MRGPRX4LTB4RLTB4R2 | |
| SCHEMBL2935431 | 0.86 | P2RY14 (0.61) | P2RY14ALOX5NR1H4LTB4RLTB4R2 | |
| SCHEMBL2927585 | 0.84 | P2RY14 (0.59) | P2RY14FFAR1ALOX5LTB4RLTB4R2 | |
| SCHEMBL2933902 | 0.84 | P2RY14 (0.59) | P2RY14ALOX5MRGPRX4NR1H4LTB4R | |
| SCHEMBL2929206 | 0.83 | P2RY14 (0.58) | P2RY14ALOX5 | |
| SCHEMBL2933139 | 0.80 | P2RY14 (0.56) | P2RY14ALOX5MRGPRX4LTB4RLTB4R2 | |
| SCHEMBL13057709 | 0.80 | P2RY14 (0.53) | P2RY14MRGPRX4LTB4RLTB4R2 | |
| SCHEMBL2957088 | 0.79 | P2RY14 (0.53) | P2RY14ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2229373-A1 | SUBSTITUTED 2-NAPHTHOIC ACIDS AS ANTAGONISTS OF GPR105 ACTIVITY | Merck Frosst Canada Ltd. (CA) | 2010-09-22 | — | — | EP | disclosed |
| WO-2009070873-A1 | SUBSTITUTED 2-NAPHTHOIC ACIDS AS ANTAGONISTS OF GPR105 ACTIVITY | MERCK FROSST CANADA LTD. (CA) | 2009-06-11 | — | — | WO | disclosed |