SCHEMBL29293144

SCHEMBL29293144

c1ccc(-c2cccc3c2sc2c(-c4cc(-c5ccncc5)nc(-c5ccncc5)c4)cccc23)cc1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 3/20 0.49
ALDH1A1 P00352 3/20 0.49
MAPT P10636 3/20 0.49
HPGD P15428 1/20 0.49
KMT2A Q03164 2/20 0.48
MAPK1 P28482 1/20 0.48
MEN1 O00255 1/20 0.48
LMNA P02545 1/20 0.48
RECQL P46063 1/20 0.48
NPSR1 Q6W5P4 1/20 0.48
SQOR Q9Y6N5 1/20 0.45
LIMK1 P53667 1/20 0.44
TNF P01375 1/20 0.42
AR P10275 1/20 0.42
CYP17A1 P05093 1/20 0.41
CYP1A2 P05177 1/20 0.41
DHODH Q02127 1/20 0.41
PDE10A Q9Y233 2/20 0.41
GSK3B P49841 2/20 0.40
CDC7 O00311 2/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29293101 0.97 KDM4E (0.47) KDM4EALDH1A1MAPTHPGDKMT2A
SCHEMBL29293023 0.93 LIMK1 (0.49) KDM4EALDH1A1MAPTHPGDKMT2A
SCHEMBL29293177 0.90 LIMK1 (0.47) KDM4EALDH1A1MAPTHPGDKMT2A
SCHEMBL29293349 0.88 CYP19A1 (0.52) KDM4EALDH1A1MAPTHPGDKMT2A
SCHEMBL29293020 0.88 LIMK1 (0.53) KDM4EALDH1A1MAPTHPGDMAPK1
SCHEMBL29293143 0.87 NOTUM (0.47) KDM4EALDH1A1MAPTHPGDKMT2A
SCHEMBL29293100 0.87 LIMK1 (0.47) KDM4EMAPTKMT2AMEN1LIMK1
SCHEMBL29293162 0.86 CYP19A1 (0.59) KDM4EALDH1A1MAPTHPGDLMNA
SCHEMBL29293200 0.86 MEN1 (0.47) KDM4EALDH1A1MAPTHPGDKMT2A
SCHEMBL29293099 0.85 NOTUM (0.52) KDM4EALDH1A1MAPTHPGDMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240228470-A1 Organic Compound And Organic Light Emitting Device Including Same P&H TECH CO., LTD (KR) 2024-07-11 US disclosed
US-20240228470-A1 Organic Compound And Organic Light Emitting Device Including Same P&H TECH CO., LTD (KR) 2024-07-11 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240228470-A1 Organic Compound And Organic Light Emitting Device Including Same OR10J3, ORMDL3, OR51E2 KDM4E 807/4885ALDH1A1 249/4885MAPT 570/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.