SCHEMBL29293180

SCHEMBL29293180

c1ccc(-c2cccc3c2sc2c(-c4cc(-c5ccccc5-c5cccnc5)cc(-c5ccccc5-c5cccnc5)c4)cccc23)cc1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP11B1 P15538 3/20 0.49
LIMK1 P53667 1/20 0.45
PTGS2 P35354 1/20 0.44
CYP2A6 P11509 2/20 0.44
ALDH1A1 P00352 2/20 0.43
MAPT P10636 2/20 0.43
POLB P06746 1/20 0.43
TSHR P16473 1/20 0.43
PDE10A Q9Y233 1/20 0.43
TNF P01375 1/20 0.43
DHPS P49366 1/20 0.42
CYP17A1 P05093 1/20 0.42
CYP1A2 P05177 1/20 0.42
CYP11B2 P19099 2/20 0.41
ALOX5 P09917 2/20 0.41
RPS6KA3 P51812 1/20 0.41
GPR84 Q9NQS5 1/20 0.41
KMO O15229 1/20 0.41
KDM4E B2RXH2 1/20 0.41
HPGD P15428 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29293150 0.94 CYP11B1 (0.45) CYP11B1LIMK1CYP2A6ALDH1A1MAPT
SCHEMBL29293019 0.94 CYP11B1 (0.50) CYP11B1LIMK1PTGS2CYP2A6ALDH1A1
SCHEMBL29293147 0.93 CYP1A2 (0.42) CYP11B1LIMK1PTGS2CYP2A6ALDH1A1
SCHEMBL29293084 0.93 CYP11B1 (0.46) CYP11B1LIMK1PTGS2CYP2A6ALDH1A1
SCHEMBL29293034 0.92 CYP19A1 (0.45) CYP11B1LIMK1PTGS2CYP2A6ALDH1A1
SCHEMBL29293145 0.92 CYP19A1 (0.45) CYP11B1LIMK1PTGS2CYP2A6ALDH1A1
SCHEMBL29293175 0.92 CYP19A1 (0.45) CYP11B1LIMK1PTGS2CYP2A6ALDH1A1
SCHEMBL29293214 0.92 CYP19A1 (0.45) CYP11B1LIMK1PTGS2CYP2A6ALDH1A1
SCHEMBL29293082 0.91 CYP11B1 (0.45) CYP11B1LIMK1CYP2A6ALDH1A1MAPT
SCHEMBL29293249 0.91 CYP11B1 (0.47) CYP11B1LIMK1PTGS2CYP2A6ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240228470-A1 Organic Compound And Organic Light Emitting Device Including Same P&H TECH CO., LTD (KR) 2024-07-11 US disclosed
US-20240228470-A1 Organic Compound And Organic Light Emitting Device Including Same P&H TECH CO., LTD (KR) 2024-07-11 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240228470-A1 Organic Compound And Organic Light Emitting Device Including Same OR10J3, ORMDL3, OR51E2 CYP11B1 1292/4885LIMK1 75/4885PTGS2 3462/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.