Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS3 | P29474 | 4/20 | 0.41 |
| ▸ | NOS2 | P35228 | 4/20 | 0.41 |
| ▸ | NOS1 | P29475 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.37 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.36 |
| ▸ | TLR9 | Q9NR96 | 2/20 | 0.33 |
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.33 |
| ▸ | TLR7 | Q9NYK1 | 2/20 | 0.33 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.33 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.33 |
| ▸ | TAS1R2 | Q8TE23 | 2/20 | 0.33 |
| ▸ | JAK2 | O60674 | 1/20 | 0.33 |
| ▸ | JAK1 | P23458 | 1/20 | 0.33 |
| ▸ | TYK2 | P29597 | 1/20 | 0.33 |
| ▸ | JAK3 | P52333 | 1/20 | 0.33 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.33 |
| ▸ | GABRP | O00591 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18192105 | 0.80 | AR (0.40) | NOS3NOS2NOS1KDM4EMEN1 | |
| SCHEMBL15465077 | 0.80 | AR (0.40) | NOS3NOS2NOS1KDM4EMEN1 | |
| SCHEMBL15465075 | 0.80 | AR (0.40) | NOS3NOS2NOS1KDM4EMEN1 | |
| SCHEMBL4539765 | 0.78 | NR3C2 (0.60) | NOS3NOS2NOS1KDM4EMEN1 | |
| SCHEMBL4539761 | 0.78 | NR3C2 (0.60) | NOS3NOS2NOS1KDM4EMEN1 | |
| SCHEMBL4539768 | 0.78 | NR3C2 (0.60) | NOS3NOS2NOS1KDM4EMEN1 | |
| SCHEMBL22272915 | 0.77 | BACE1 (0.49) | NOS3NOS2NOS1KDM4EMEN1 | |
| SCHEMBL15465530 | 0.77 | AR (0.38) | NOS3NOS2NOS1KDM4EMEN1 | |
| SCHEMBL18192120 | 0.77 | AR (0.38) | NOS3NOS2NOS1KDM4EMEN1 | |
| SCHEMBL15465527 | 0.77 | AR (0.38) | NOS3NOS2NOS1KDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3143026-B1 | COMPOUNDS AND COMPOSITIONS FOR INDUCING CHONDROGENESIS | NOVARTIS AG (CH) | 2024-07-10 | — | — | EP | disclosed |