SCHEMBL29295647

SCHEMBL29295647

CCC(C)COCC(C)CCNC

nearest known ligand 0.30

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14587932 0.84 HTR2A (0.30)
SCHEMBL12037849 0.83 KDM4E (0.30) KDM4E
SCHEMBL14303262 0.81
SCHEMBL4153435 0.81
SCHEMBL22340384 0.80 HSD17B10 (0.33) KDM4E
SCHEMBL10707675 0.78 MAPT (0.34) KDM4E
SCHEMBL10707670 0.78 MAPT (0.34) KDM4E
SCHEMBL596042 0.78 MAPT (0.34) KDM4E
SCHEMBL1638639 0.78 MAPT (0.34) KDM4E
SCHEMBL2625060 0.77 EPHX1 (0.34) KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024148308-A1 NOVEL, REVERSIBLE DPP1 INHIBITORS AND USES THEREOF INSMED INCORPORATED (US) 2024-07-11 WO disclosed