Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.76 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.76 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.76 |
| ▸ | PAOX | Q6QHF9 | 3/20 | 0.61 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.59 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | EPHX1 | P07099 | 5/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | NAMPT | P43490 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.41 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28428421 | 1.00 | KDM4E (0.76) | KDM4EMAPK1HIF1APAOXADRA1A | |
| SCHEMBL10528699 | 1.00 | KDM4E (0.76) | KDM4EMAPK1HIF1APAOXADRA1A | |
| SCHEMBL7688233 | 1.00 | KDM4E (0.76) | KDM4EMAPK1HIF1APAOXADRA1A | |
| SCHEMBL294051 | 0.98 | — | — | |
| SCHEMBL211011 | 0.90 | — | — | |
| SCHEMBL6516953 | 0.87 | KDM4E (1.00) | KDM4EMAPK1HIF1APAOXADRA1A | |
| SCHEMBL14740196 | 0.87 | KDM4E (1.00) | KDM4EMAPK1HIF1APAOXADRA1A | |
| SCHEMBL1847535 | 0.87 | KDM4E (1.00) | KDM4EMAPK1HIF1APAOXADRA1A | |
| SCHEMBL1900654 | 0.87 | KDM4E (1.00) | KDM4EMAPK1HIF1APAOXADRA1A | |
| SCHEMBL14739904 | 0.87 | KDM4E (1.00) | KDM4EMAPK1HIF1APAOXADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 149 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11191270-B2 | Pesticide composition comprising a tetrazolyloxime derivative and a fungicide or an insecticide active substance | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2021-12-07 | — | — | US | claimed |
| US-20190104736-A1 | PESTICIDE COMPOSITION COMPRISING A TETRAZOLYLOXIME DERIVATIVE AND A FUNGICIDE OR AN INSECTICIDE ACTIVE SUBSTANCE | BAYER CROPSCIENCE AG (DE) | 2019-04-11 | — | — | US | claimed |
| US-10188106-B2 | Pesticide composition comprising a tetrazolyloxime derivative and a fungicide or an insecticide active substance | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2019-01-29 | — | — | US | claimed |
| EP-3256471-B1 | NOVEL 2-OXO-6,7-DIHYDROBENZO[A]QUINOLIZINE-3-CARBOXYLIC ACID DERIVATIVES FOR THE TREATMENT AND PROPHYLAXIS OF HEPATITIS B VIRUS INFECTION | HOFFMANN LA ROCHE (CH) | 2018-12-12 | — | — | EP | claimed |
| US-10093671-B2 | 2-oxo-6,7-dihydrobenzo[a]quinolizine-3-carboxylic acid derivatives for the treatment and prophylaxis of hepatitis B virus infection | HOFFMANN-LA ROCHE INC. (US) | 2018-10-09 | — | — | US | claimed |
| EP-3256471-A1 | NOVEL 2-OXO-6,7-DIHYDROBENZO[A]QUINOLIZINE-3-CARBOXYLIC ACID DERIVATIVES FOR THE TREATMENT AND PROPHYLAXIS OF HEPATITIS B VIRUS INFECTION | F. Hoffmann-La Roche AG (CH) | 2017-12-20 | — | — | EP | claimed |
| US-20170342069-A1 | NOVEL 2-OXO-6, 7-DIHYDROBENZO[a]QUINOLIZINE-3-CARBOXYLIC ACID DERIVATIVES FOR THE TREATMENT AND PROPHYLAXIS OF HEPATITIS B VIRUS INFECTION | HOFFMANN-LA ROCHE INC. (US) | 2017-11-30 | — | — | US | claimed |
| EP-3088389-A1 | 4-EPI-ISOFAGOMINE DERIVATIVES | Dorphan S.A. (CH) | 2016-11-02 | — | — | EP | claimed |
| WO-2016128335-A1 | NOVEL 2-OXO-6,7-DIHYDROBENZO[A]QUINOLIZINE-3-CARBOXYLIC ACID DERIVATIVES FOR THE TREATMENT AND PROPHYLAXIS OF HEPATITIS B VIRUS INFECTION | F. HOFFMANN-LA ROCHE AG (CH) | 2016-08-18 | — | — | WO | claimed |
| US-20150257387-A1 | PESTICIDE COMPOSITION COMPRISING A TETRAZOLYLOXIME DERIVATIVE AND A FUNGICIDE OR AN INSECTICIDE ACTIVE SUBSTANCE | BAYER CROPSCIENCE AG (DE) | 2015-09-17 | — | — | US | claimed |
| US-9060518-B2 | Pesticide composition comprising a tetrazolyloxime derivative and a fungicide or an insecticide active substance | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2015-06-23 | — | — | US | claimed |
| CN-104381270-A | PESTICIDE COMPOSITION COMPRISING A TETRAZOLYLOXIME DERIVATIVE AND A FUNGICIDE OR AN INSECTICIDE ACTIVE SUBSTANCE | BAYER CROPSCIENCE AG | 2015-03-04 | — | — | CN | claimed |
| JP-2011509971-A | — | — | 2011-03-31 | — | — | JP | claimed |
| US-20110052555-A1 | PESTICIDE COMPOSITION COMPRISING A TETRAZOLYLOXIME DERIVATIVE AND A FUNGICIDE OR AN INSECTICIDE ACTIVE SUBSTANCE | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2011-03-03 | — | — | US | claimed |
| CN-101977501-A | Pesticidal compositions comprising tetrazolyloxime derivatives and fungicidal or insecticidal active substances | BAYER CROPSCIENCE AG | 2011-02-16 | — | — | CN | claimed |
| EP-2234489-A2 | PESTICIDE COMPOSITION COMPRISING A TETRAZOLYLOXIME DERIVATIVE AND A FUNGICIDE OR AN INSECTICIDE ACTIVE SUBSTANCE | Bayer CropScience AG (DE) | 2010-10-06 | — | — | EP | claimed |
| WO-2009090181-A2 | PESTICIDE COMPOSITION COMPRISING A TETRAZOLYLOXIME DERIVATIVE AND A FUNGICIDE OR AN INSECTICIDE ACTIVE SUBSTANCE | BAYER CROPSCIENCE SA (FR) | 2009-07-23 | — | — | WO | claimed |
| US-4315855-A | Monoazo disperse dyes containing a nitrophenyl group and a homophthalimide group | BASF AKTIENGESELLSCHAFT (DE) | 1982-02-16 | — | — | US | claimed |
| EP-4219477-A1 | CYANOTRIAZOLE COMPOUNDS | Otsuka Pharmaceutical Co., Ltd. (JP) | 2023-08-02 | — | — | EP | disclosed |
| US-4315855-A | Monoazo disperse dyes containing a nitrophenyl group and a homophthalimide group | BASF AKTIENGESELLSCHAFT (DE) | 1982-02-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11191270-B2 | Pesticide composition comprising a tetrazolyloxime derivative and a fungicide or an insecticide active substance | DDT, TH, PRDX5 | KDM4E 2173/4885MAPK1 4598/4885HIF1A 4692/4885 |
| US-20170342069-A1 | NOVEL 2-OXO-6, 7-DIHYDROBENZO[a]QUINOLIZINE-3-CARBOXYLIC ACID DERIVATIVES FOR THE TREATMENT AND PROPHYLAXIS OF HEPATITIS B VIRUS INFECTION | HAVCR2, CYP2B6, CYP2A6 | KDM4E 2672/4885MAPK1 2785/4885HIF1A 1193/4885 |
| US-20110052555-A1 | PESTICIDE COMPOSITION COMPRISING A TETRAZOLYLOXIME DERIVATIVE AND A FUNGICIDE OR AN INSECTICIDE ACTIVE SUBSTANCE | DDT, TH, PRDX5 | KDM4E 2173/4885MAPK1 4598/4885HIF1A 4692/4885 |
| US-20150257387-A1 | PESTICIDE COMPOSITION COMPRISING A TETRAZOLYLOXIME DERIVATIVE AND A FUNGICIDE OR AN INSECTICIDE ACTIVE SUBSTANCE | DDT, TH, PRDX5 | KDM4E 2173/4885MAPK1 4598/4885HIF1A 4692/4885 |
| US-10093671-B2 | 2-oxo-6,7-dihydrobenzo[a]quinolizine-3-carboxylic acid derivatives for the treatment and prophylaxis of hepatitis B virus infection | HAVCR2, CYP2B6, CYP2A6 | KDM4E 2436/4885MAPK1 3258/4885HIF1A 1182/4885 |
| US-20190104736-A1 | PESTICIDE COMPOSITION COMPRISING A TETRAZOLYLOXIME DERIVATIVE AND A FUNGICIDE OR AN INSECTICIDE ACTIVE SUBSTANCE | DDT, TH, PRDX5 | KDM4E 2173/4885MAPK1 4598/4885HIF1A 4692/4885 |
| US-10188106-B2 | Pesticide composition comprising a tetrazolyloxime derivative and a fungicide or an insecticide active substance | DDT, TH, PRDX5 | KDM4E 2173/4885MAPK1 4598/4885HIF1A 4692/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.