Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AVPR2 | P30518 | 10/20 | 0.59 |
| ▸ | OXTR | P30559 | 1/20 | 0.55 |
| ▸ | AVPR1A | P37288 | 8/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1346112 | 0.88 | AVPR2 (0.63) | AVPR2OXTRAVPR1A | |
| SCHEMBL2929911 | 0.86 | AVPR2 (0.59) | AVPR2OXTRAVPR1A | |
| SCHEMBL1344819 | 0.85 | AVPR2 (0.60) | AVPR2OXTRAVPR1A | |
| SCHEMBL2930335 | 0.83 | AVPR2 (0.59) | AVPR2OXTRAVPR1A | |
| SCHEMBL1346201 | 0.82 | AVPR2 (0.57) | AVPR2OXTRAVPR1A | |
| SCHEMBL1345989 | 0.82 | AVPR2 (0.54) | AVPR2OXTRAVPR1A | |
| SCHEMBL1345991 | 0.82 | AVPR2 (0.54) | AVPR2OXTRAVPR1A | |
| SCHEMBL1346491 | 0.81 | AVPR2 (0.58) | AVPR2OXTRAVPR1A | |
| SCHEMBL1346294 | 0.81 | AVPR2 (0.56) | AVPR2OXTRAVPR1A | |
| SCHEMBL1346750 | 0.81 | AVPR2 (0.56) | AVPR2OXTRAVPR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1778677-B1 | HETEROCYCLIC CONDENSED COMPOUNDS USEFUL AS ANTIDIURETIC AGENTS | VANTIA LTD (GB) | 2010-02-03 | — | — | EP | claimed |
| EP-1778677-B1 | HETEROCYCLIC CONDENSED COMPOUNDS USEFUL AS ANTIDIURETIC AGENTS | VANTIA LTD (GB) | 2010-02-03 | — | — | EP | disclosed |