SCHEMBL29299447

SCHEMBL29299447

NCc1cc(O)c(N2CC(=O)NS2(=O)=O)c(F)c1

nearest known ligand 0.68

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
PTPN1 P18031 6/20 0.68
PTPN2 P17706 19/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31758187 1.00 PTPN1 (0.68) PTPN1PTPN2
SCHEMBL31758184 0.91 PTPN1 (0.67) PTPN1PTPN2
SCHEMBL12009129 0.87 PTPN1 (0.68) PTPN1PTPN2
SCHEMBL2897202 0.83 PTPN1 (0.63) PTPN1PTPN2
SCHEMBL31758035 0.83 PTPN1 (0.60) PTPN1PTPN2
SCHEMBL3128181 0.82 PTPN1 (0.61) PTPN1PTPN2
SCHEMBL30705410 0.82 PTPN1 (0.78) PTPN1PTPN2
SCHEMBL12009130 0.82 PTPN1 (0.98) PTPN1PTPN2
SCHEMBL12009128 0.82 PTPN1 (0.94) PTPN1PTPN2
SCHEMBL25326795 0.81 PTPN1 (0.61) PTPN1PTPN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240228476-A1 INHIBITORS OF PROTEIN TYROSINE PHOSPHATASE, COMPOSITIONS, AND METHODS OF USE BRISTOL-MYERS SQUIBB COMPANY (US) 2024-07-11 US disclosed
US-20240228476-A1 INHIBITORS OF PROTEIN TYROSINE PHOSPHATASE, COMPOSITIONS, AND METHODS OF USE BRISTOL-MYERS SQUIBB COMPANY (US) 2024-07-11 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240228476-A1 INHIBITORS OF PROTEIN TYROSINE PHOSPHATASE, COMPOSITIONS, AND METHODS OF USE PTPN2, PTPN22, PTPN1 PTPN1 3/4885PTPN2 1/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.