SCHEMBL29299489

SCHEMBL29299489

CC(C)C(=O)NCc1cn(-c2ccccc2)nn1

nearest known ligand 0.65

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
MIF P14174 1/20 0.58
GLA P06280 1/20 0.55
NOTUM Q6P988 2/20 0.54
L3MBTL1 Q9Y468 1/20 0.54
NPC1 O15118 1/20 0.51
MAOA P21397 1/20 0.50
CAPN1 P07384 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26502680 0.87 MIF (0.54) MIFGLACAPN1
SCHEMBL29300000 0.85 NOTUM (0.66) MIFGLANOTUML3MBTL1NPC1
SCHEMBL19755670 0.84 CYP2D6 (0.51) MIFGLANOTUML3MBTL1NPC1
SCHEMBL28504779 0.79
SCHEMBL28504778 0.79
SCHEMBL27430511 0.78 CA1 (0.72) MIFGLANOTUML3MBTL1NPC1
SCHEMBL22917015 0.77 KCNJ1 (0.40)
SCHEMBL19655507 0.76 ANPEP (0.41)
SCHEMBL22861720 0.73 GBA1 (0.44)
SCHEMBL18965360 0.73 NOTUM (0.62) MIFGLANOTUML3MBTL1NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240226343-A1 NEUROPEPTIDE Y1 RECEPTOR (NPY1R) TARGETED THERAPEUTICS AND USES THEREOF RADIONETICS ONCOLOGY, INC. 2024-07-11 US disclosed
US-20240226343-A1 NEUROPEPTIDE Y1 RECEPTOR (NPY1R) TARGETED THERAPEUTICS AND USES THEREOF RADIONETICS ONCOLOGY, INC. 2024-07-11 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240226343-A1 NEUROPEPTIDE Y1 RECEPTOR (NPY1R) TARGETED THERAPEUTICS AND USES THEREOF NPY1R, NPY2R, NPY4R MIF 4111/4885GLA 1800/4885NOTUM 4807/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.