Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCR4 | P61073 | 1/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | GFER | P55789 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31679393 | 0.91 | CXCR4 (0.67) | CXCR4KDM4EALDH1A1MAPTTSHR | |
| SCHEMBL29892433 | 0.91 | CXCR4 (0.67) | CXCR4KDM4EALDH1A1MAPTTSHR | |
| SCHEMBL22009968 | 0.91 | CXCR4 (0.67) | CXCR4KDM4EALDH1A1MAPTTSHR | |
| SCHEMBL16705675 | 0.90 | KDM4E (0.61) | KDM4EALDH1A1NPSR1L3MBTL1LMNA | |
| SCHEMBL26908105 | 0.90 | CXCR4 (0.69) | CXCR4KDM4EALDH1A1MAPTTSHR | |
| SCHEMBL31679380 | 0.90 | CXCR4 (0.69) | CXCR4KDM4EALDH1A1MAPTTSHR | |
| SCHEMBL465725 | 0.90 | CXCR4 (0.69) | CXCR4KDM4EALDH1A1MAPTTSHR | |
| SCHEMBL29978069 | 0.86 | CXCR4 (0.51) | CXCR4KDM4EALDH1A1NPSR1L3MBTL1 | |
| SCHEMBL23665112 | 0.85 | CXCR4 (0.58) | CXCR4KDM4EALDH1A1LMNAMAPT | |
| SCHEMBL28431330 | 0.84 | KDM4E (0.55) | KDM4EALDH1A1NPSR1L3MBTL1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240226343-A1 | NEUROPEPTIDE Y1 RECEPTOR (NPY1R) TARGETED THERAPEUTICS AND USES THEREOF | RADIONETICS ONCOLOGY, INC. | 2024-07-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240226343-A1 | NEUROPEPTIDE Y1 RECEPTOR (NPY1R) TARGETED THERAPEUTICS AND USES THEREOF | NPY1R, NPY2R, NPY4R | CXCR4 123/4885KDM4E 3543/4885ALDH1A1 3906/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.