Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 11/20 | 0.47 |
| ▸ | MEN1 | O00255 | 10/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 10/20 | 0.47 |
| ▸ | RAB9A | P51151 | 9/20 | 0.47 |
| ▸ | NPC1 | O15118 | 9/20 | 0.47 |
| ▸ | MAPT | P10636 | 7/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 7/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.47 |
| ▸ | TP53 | P04637 | 3/20 | 0.47 |
| ▸ | MITF | O75030 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 12/20 | 0.45 |
| ▸ | HPGD | P15428 | 10/20 | 0.45 |
| ▸ | LMNA | P02545 | 4/20 | 0.45 |
| ▸ | CLK1 | P49759 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 3/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | CASP1 | P29466 | 2/20 | 0.38 |
| ▸ | CASP7 | P55210 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL5473424 | 0.99 | KDM4E (0.48) | KDM4EMEN1KMT2ARAB9ANPC1 | |
| Hydrochloric Acid SCHEMBL6853820 | 0.99 | KDM4E (0.46) | KDM4EMEN1KMT2ARAB9ANPC1 | |
| Hydrochloric Acid SCHEMBL6853812 | 0.98 | KDM4E (0.47) | KDM4EMEN1KMT2ARAB9ANPC1 | |
| SCHEMBL7004934 | 0.85 | KDM4E (0.43) | KDM4EMEN1KMT2ARAB9ANPC1 | |
| Hydrochloric Acid SCHEMBL6850196 | 0.84 | KDM4E (0.45) | KDM4EMEN1KMT2ARAB9ANPC1 | |
| SCHEMBL3946877 | 0.78 | KMT2A (0.50) | KDM4EMEN1KMT2ARAB9ANPC1 | |
| SCHEMBL26912937 | 0.77 | KDM4E (0.70) | KDM4EMEN1KMT2ARAB9ANPC1 | |
| Hydrochloric Acid SCHEMBL8150702 | 0.77 | KMT2A (0.49) | KDM4EMEN1KMT2ARAB9ANPC1 | |
| Hydrochloric Acid SCHEMBL6266640 | 0.77 | KDM4E (0.45) | KDM4EMEN1KMT2ARAB9ANPC1 | |
| Hydrochloric Acid SCHEMBL6266636 | 0.75 | KDM4E (0.45) | KDM4EMEN1KMT2ARAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1334713-B1 | Dyeing composition comprising diaminopyrazole and cationic compounds as oxidation bases and a coupling agent | OREAL (FR) | 2005-12-07 | — | — | EP | claimed |
| EP-1334713-A1 | Dyeing composition comprising diaminopyrazole and cationic compounds as oxidation bases and a coupling agent | L'OREAL (FR) | 2003-08-13 | — | — | EP | claimed |
| EP-1147109-B1 | NOVEL CATIONIC OXIDATION BASES, THEIR USE FOR OXIDATIVE DYEING OF KERATIN FIBRES, DYEING COMPOSITIONS AND DYEING METHODS | OREAL (FR) | 2003-04-02 | — | — | EP | claimed |
| EP-1147109-A1 | NOVEL CATIONIC OXIDATION BASES, THEIR USE FOR OXIDATION DYEING OF KERATIN FIBRES, DYEING COMPOSITIONS ET DYEING METHODS | L'OREAL (FR) | 2001-10-24 | — | — | EP | claimed |
| WO-2000043396-A1 | NOVEL CATIONIC OXIDATION BASES, THEIR USE FOR OXIDATION DYEING OF KERATIN FIBRES, DYEING COMPOSITIONS ET DYEING METHODS | L'OREAL (FR) | 2000-07-27 | — | — | WO | claimed |
| EP-1728500-B1 | Composition for dyeing keratinic fibres comprising a diamino-N,N-dihydro-pyrazolon derivative and a cationic oxidation dye | OREAL (FR) | 2010-01-27 | — | — | EP | disclosed |
| EP-1728500-A1 | Composition for dyeing keratinic fibres comprising a diamino-N,N-dihydro-pyrazolon derivative and a cationic oxidation dye | L'OREAL (FR) | 2006-12-06 | — | — | EP | disclosed |
| EP-1334713-B1 | Dyeing composition comprising diaminopyrazole and cationic compounds as oxidation bases and a coupling agent | OREAL (FR) | 2005-12-07 | — | — | EP | disclosed |
| EP-1334713-A1 | Dyeing composition comprising diaminopyrazole and cationic compounds as oxidation bases and a coupling agent | L'OREAL (FR) | 2003-08-13 | — | — | EP | disclosed |
| EP-1147109-B1 | NOVEL CATIONIC OXIDATION BASES, THEIR USE FOR OXIDATIVE DYEING OF KERATIN FIBRES, DYEING COMPOSITIONS AND DYEING METHODS | OREAL (FR) | 2003-04-02 | — | — | EP | disclosed |
| EP-1147109-A1 | NOVEL CATIONIC OXIDATION BASES, THEIR USE FOR OXIDATION DYEING OF KERATIN FIBRES, DYEING COMPOSITIONS ET DYEING METHODS | L'OREAL (FR) | 2001-10-24 | — | — | EP | disclosed |
| WO-2000043396-A1 | NOVEL CATIONIC OXIDATION BASES, THEIR USE FOR OXIDATION DYEING OF KERATIN FIBRES, DYEING COMPOSITIONS ET DYEING METHODS | L'OREAL (FR) | 2000-07-27 | — | — | WO | disclosed |