Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 1/20 | 0.50 |
| ▸ | CXCR4 | P61073 | 3/20 | 0.43 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | FUCA1 | P04066 | 1/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | MAN1B1 | Q9UKM7 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21574014 | 0.88 | HTR2C (0.53) | HTR2CCXCR4HTR2AFUCA1MEN1 | |
| SCHEMBL2019717 | 0.83 | HTR2C (0.64) | HTR2CCXCR4HTR2AFUCA1MEN1 | |
| SCHEMBL2019718 | 0.83 | HTR2C (0.64) | HTR2CCXCR4HTR2AFUCA1MEN1 | |
| Hydrochloric Acid SCHEMBL4523862 | 0.81 | HTR2C (0.62) | HTR2CCXCR4HTR2AFUCA1MEN1 | |
| SCHEMBL2934330 | 0.74 | CXCR4 (0.69) | HTR2CCXCR4HTR2ASIGMAR1MEN1 | |
| SCHEMBL16083006 | 0.74 | CXCR4 (0.69) | HTR2CCXCR4HTR2ASIGMAR1MEN1 | |
| SCHEMBL17656855 | 0.73 | CXCR4 (0.59) | HTR2CCXCR4HTR2AFUCA1SIGMAR1 | |
| SCHEMBL23710731 | 0.71 | SAT1 (0.37) | — | |
| SCHEMBL5519379 | 0.68 | CXCR4 (0.61) | HTR2CCXCR4HTR2ASIGMAR1MEN1 | |
| SCHEMBL7330860 | 0.68 | CXCR4 (0.61) | HTR2CCXCR4HTR2ASIGMAR1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024148029-A2 | ORGANIC COMPOUNDS AS NLRP3 INHIBITORS | KODIAK SCIENCES INC. (US) | 2024-07-11 | — | — | WO | disclosed |