Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 19/20 | 0.64 |
| ▸ | HDAC8 | Q9BY41 | 4/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.39 |
| ▸ | HDAC7 | Q8WUI4 | 3/20 | 0.39 |
| ▸ | HDAC11 | Q96DB2 | 3/20 | 0.39 |
| ▸ | HDAC9 | Q9UKV0 | 3/20 | 0.39 |
| ▸ | HDAC5 | Q9UQL6 | 3/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 5/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.34 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.34 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.34 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20535302 | 0.79 | HDAC6 (1.00) | HDAC6HDAC8HDAC4HDAC7HDAC11 | |
| SCHEMBL24401416 | 0.72 | HDAC6 (0.69) | HDAC6HDAC8HDAC4HDAC7HDAC11 | |
| SCHEMBL20535298 | 0.66 | HDAC6 (0.72) | HDAC6HDAC8HDAC4HDAC7HDAC11 | |
| SCHEMBL29309846 | 0.66 | HDAC6 (0.60) | HDAC6HDAC8HDAC1HDAC3HDAC2 | |
| SCHEMBL20534929 | 0.65 | HDAC6 (1.00) | HDAC6HDAC8HDAC4HDAC7HDAC11 | |
| SCHEMBL30096073 | 0.65 | HDAC6 (0.72) | HDAC6HDAC8HDAC4HDAC7HDAC11 | |
| SCHEMBL24401364 | 0.61 | HDAC6 (0.53) | HDAC6HDAC8HDAC4HDAC7HDAC11 | |
| SCHEMBL29309855 | 0.60 | HDAC6 (0.62) | HDAC6HDAC8HDAC4HDAC7HDAC11 | |
| SCHEMBL29309837 | 0.60 | HDAC6 (0.47) | HDAC6HDAC8HDAC4HDAC7HDAC11 | |
| SCHEMBL24401272 | 0.58 | HDAC6 (0.45) | HDAC6HDAC8HDAC4HDAC7HDAC11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4397656-A2 | HDAC6 INHIBITORS AND IMAGING AGENTS | The General Hospital Corporation (US) | 2024-07-10 | — | — | EP | disclosed |