Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 12/20 | 0.54 |
| ▸ | HDAC3 | O15379 | 11/20 | 0.54 |
| ▸ | HDAC1 | Q13547 | 11/20 | 0.54 |
| ▸ | HDAC8 | Q9BY41 | 8/20 | 0.54 |
| ▸ | HDAC2 | Q92769 | 8/20 | 0.54 |
| ▸ | HDAC5 | Q9UQL6 | 7/20 | 0.54 |
| ▸ | HDAC4 | P56524 | 6/20 | 0.54 |
| ▸ | HDAC10 | Q969S8 | 4/20 | 0.54 |
| ▸ | KDM1A | O60341 | 2/20 | 0.42 |
| ▸ | MAOA | P21397 | 2/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.40 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.40 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.40 |
| ▸ | MEF2D | Q14814 | 1/20 | 0.39 |
| ▸ | BCHE | P06276 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17483891 | 0.79 | HDAC1 (0.71) | HDAC6HDAC3HDAC1HDAC8HDAC2 | |
| SCHEMBL23054865 | 0.75 | HDAC3 (0.75) | HDAC6HDAC3HDAC1HDAC8HDAC2 | |
| SCHEMBL19682899 | 0.74 | HDAC6 (0.61) | HDAC6HDAC3HDAC1HDAC8HDAC2 | |
| SCHEMBL22951073 | 0.73 | HDAC6 (0.72) | HDAC6HDAC3HDAC1HDAC8HDAC2 | |
| SCHEMBL12592142 | 0.73 | HDAC3 (0.71) | HDAC6HDAC3HDAC1HDAC8HDAC2 | |
| SCHEMBL17483934 | 0.73 | HDAC6 (0.65) | HDAC6HDAC3HDAC1HDAC8HDAC2 | |
| SCHEMBL12150981 | 0.71 | HDAC6 (1.00) | HDAC6HDAC3HDAC1HDAC8HDAC2 | |
| SCHEMBL21241377 | 0.71 | HDAC6 (0.59) | HDAC6HDAC3HDAC1HDAC8HDAC2 | |
| SCHEMBL19666006 | 0.70 | HDAC6 (1.00) | HDAC6HDAC3HDAC1HDAC8HDAC2 | |
| SCHEMBL16653780 | 0.70 | HDAC6 (1.00) | HDAC6HDAC3HDAC1HDAC8HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4397656-A2 | HDAC6 INHIBITORS AND IMAGING AGENTS | The General Hospital Corporation (US) | 2024-07-10 | — | — | EP | disclosed |