Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 4/20 | 0.48 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | HTR2C | P28335 | 1/20 | 0.41 |
| ▸ | HTR2B | P41595 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | PARP2 | Q9UGN5 | 5/20 | 0.40 |
| ▸ | PARP1 | P09874 | 7/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.39 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29323541 | 0.90 | CRBN (0.48) | CRBNHTR2AHTR2CHTR2BMEN1 | |
| SCHEMBL25675982 | 0.81 | CRBN (0.41) | CRBNHTR2AHTR2CHTR2BPARP2 | |
| SCHEMBL23816346 | 0.78 | CRBN (0.77) | CRBNDDB1ALDH1A1 | |
| SCHEMBL19503632 | 0.78 | CRBN (0.77) | CRBNDDB1ALDH1A1 | |
| SCHEMBL24501878 | 0.78 | CRBN (0.77) | CRBNDDB1ALDH1A1 | |
| SCHEMBL20365405 | 0.78 | CRBN (0.60) | CRBNKMT2ADDB1KDM4E | |
| SCHEMBL23919161 | 0.78 | CRBN (0.60) | CRBNKMT2ADDB1KDM4E | |
| SCHEMBL26141970 | 0.76 | CRBN (0.60) | CRBNHTR2AHTR2CHTR2BMEN1 | |
| SCHEMBL12716215 | 0.75 | CRBN (0.43) | CRBNHTR2AHTR2CHTR2BMEN1 | |
| SCHEMBL12716231 | 0.75 | CRBN (0.43) | CRBNHTR2AHTR2CHTR2BMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4397661-A1 | COMPOUND FOR DEGRADATION OF BCL-2 FAMILY PROTEINS AND MEDICAL APPLICATION THEREOF | Xizang Haisco Pharmaceutical Co., Ltd. (CN) | 2024-07-10 | — | — | EP | disclosed |