Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29312004 | 1.00 | NR1H4 (0.79) | NR1H4HSD17B13 | |
| SCHEMBL15929557 | 0.91 | NR1H4 (0.85) | NR1H4HSD17B13 | |
| SCHEMBL29618060 | 0.90 | NR1H4 (0.81) | NR1H4HSD17B13 | |
| SCHEMBL21715300 | 0.90 | NR1H4 (0.81) | NR1H4HSD17B13 | |
| SCHEMBL15929548 | 0.90 | NR1H4 (0.81) | NR1H4HSD17B13 | |
| SCHEMBL29880760 | 0.88 | NR1H4 (1.00) | NR1H4HSD17B13 | |
| SCHEMBL17087814 | 0.88 | NR1H4 (1.00) | NR1H4HSD17B13 | |
| SCHEMBL14641898 | 0.88 | NR1H4 (1.00) | NR1H4HSD17B13 | |
| SCHEMBL14641890 | 0.88 | NR1H4 (1.00) | NR1H4HSD17B13 | |
| SCHEMBL21683094 | 0.88 | NR1H4 (0.79) | NR1H4HSD17B13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4400503-A2 | NOVEL FXR (NR1H4) BINDING AND ACTIVITY MODULATING COMPOUNDS | Gilead Sciences, Inc. (US) | 2024-07-17 | — | — | EP | disclosed |