Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | HPGD | P15428 | 2/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | CYP19A1 | P11511 | 6/20 | 0.50 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.44 |
| ▸ | MGLL | Q99685 | 1/20 | 0.38 |
| ▸ | MBOAT4 | Q96T53 | 1/20 | 0.37 |
| ▸ | PANK3 | Q9H999 | 1/20 | 0.36 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18882595 | 1.00 | KDM4E (0.54) | KDM4EALDH1A1HPGDL3MBTL1HTT | |
| SCHEMBL23019527 | 0.98 | KDM4E (0.51) | KDM4EALDH1A1HPGDL3MBTL1HTT | |
| SCHEMBL7213728 | 0.93 | KDM4E (0.49) | KDM4EALDH1A1HPGDL3MBTL1HTT | |
| SCHEMBL8167780 | 0.88 | HSD17B10 (0.63) | KDM4EALDH1A1HPGDL3MBTL1HTT | |
| SCHEMBL17225131 | 0.88 | HSD17B10 (0.63) | KDM4EALDH1A1HPGDL3MBTL1HTT | |
| SCHEMBL7219997 | 0.86 | CYP19A1 (0.45) | KDM4EALDH1A1HPGDL3MBTL1HTT | |
| SCHEMBL12750934 | 0.83 | KCNH2 (0.44) | KDM4EALDH1A1HPGDL3MBTL1HTT | |
| SCHEMBL31354 | 0.82 | KDM4E (0.44) | KDM4EALDH1A1HPGDL3MBTL1HTT | |
| SCHEMBL8376591 | 0.80 | HSD17B10 (0.61) | KDM4EALDH1A1HPGDL3MBTL1HTT | |
| SCHEMBL9240602 | 0.79 | KDM4E (0.56) | KDM4EALDH1A1HPGDL3MBTL1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3782986-B1 | HETEROCYCLIC COMPOUND | TAKEDA PHARMACEUTICALS CO (JP) | 2024-07-10 | — | — | EP | disclosed |