Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2397505 | 0.88 | JAK2 (1.00) | JAK2JAK1 | |
| SCHEMBL2392445 | 0.87 | JAK2 (1.00) | JAK2JAK1 | |
| SCHEMBL2393878 | 0.86 | JAK2 (1.00) | JAK2JAK1 | |
| SCHEMBL29422183 | 0.85 | JAK2 (1.00) | JAK2JAK1 | |
| SCHEMBL2394032 | 0.85 | JAK2 (1.00) | JAK2JAK1 | |
| SCHEMBL2396143 | 0.85 | JAK2 (1.00) | JAK2JAK1 | |
| SCHEMBL29422249 | 0.84 | JAK2 (0.90) | JAK2JAK1 | |
| SCHEMBL2395743 | 0.84 | JAK2 (0.90) | JAK2JAK1 | |
| SCHEMBL29422147 | 0.83 | JAK2 (0.91) | JAK2JAK1 | |
| SCHEMBL2395818 | 0.83 | JAK2 (0.91) | JAK2JAK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4400172-A2 | PIPERIDIN-4-YL AZETIDINE DERIVATIVES AS JAK1 INHIBITORS | Incyte Holdings Corporation (US) | 2024-07-17 | — | — | EP | disclosed |