Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.40 |
| ▸ | CHRNB4 | P30926 | 6/20 | 0.39 |
| ▸ | CHRNA3 | P32297 | 6/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.33 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.33 |
| ▸ | SHBG | P04278 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9287662 | 1.00 | SLC6A2 (0.40) | SLC6A2SLC6A4SLC6A3CHRNB4CHRNA3 | |
| SCHEMBL25907131 | 1.00 | SLC6A2 (0.40) | SLC6A2SLC6A4SLC6A3CHRNB4CHRNA3 | |
| SCHEMBL8979972 | 0.98 | CYP1A2 (0.40) | SLC6A2SLC6A4SLC6A3CHRNB4CHRNA3 | |
| SCHEMBL16404037 | 0.94 | CHRNB4 (0.43) | SLC6A2SLC6A4SLC6A3CHRNB4CHRNA3 | |
| SCHEMBL13179117 | 0.94 | CHRNB4 (0.43) | SLC6A2SLC6A4SLC6A3CHRNB4CHRNA3 | |
| SCHEMBL18526484 | 0.82 | SLC6A2 (0.33) | SLC6A2SLC6A4SLC6A3CHRNB4CHRNA3 | |
| SCHEMBL10147710 | 0.82 | CHRNB4 (0.41) | SLC6A2SLC6A4SLC6A3CHRNB4CHRNA3 | |
| SCHEMBL21567212 | 0.81 | CYP1A2 (0.38) | SLC6A2SLC6A4SLC6A3CHRNB4CHRNA3 | |
| SCHEMBL19881825 | 0.81 | S1PR1 (0.36) | SLC6A2SLC6A4SLC6A3CYP1A2CHRNB2 | |
| SCHEMBL25620081 | 0.81 | S1PR1 (0.36) | SLC6A2SLC6A4SLC6A3CYP1A2CHRNB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024148274-A1 | COMPLEMENT INHIBITION | APELLIS PHARMACEUTICALS, INC. (US) | 2024-07-11 | — | — | WO | disclosed |