Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RY1 | P47900 | 13/20 | 0.68 |
| ▸ | ENPP1 | P22413 | 3/20 | 0.53 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.53 |
| ▸ | P2RY11 | Q96G91 | 3/20 | 0.53 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.53 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.53 |
| ▸ | P2RY6 | Q15077 | 1/20 | 0.53 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21257386 | 0.93 | P2RY1 (0.70) | P2RY1ENPP1P2RY12P2RY11P2RX1 | |
| SCHEMBL24178110 | 0.92 | P2RY1 (0.62) | P2RY1ENPP1P2RY12P2RY11P2RX1 | |
| SCHEMBL21257364 | 0.88 | P2RY1 (0.66) | P2RY1 | |
| SCHEMBL16258261 | 0.87 | P2RY1 (0.66) | P2RY1P2RY11 | |
| SCHEMBL19807561 | 0.85 | P2RY1 (0.52) | P2RY1ENPP1P2RY12P2RY11P2RX1 | |
| SCHEMBL19503291 | 0.85 | P2RY1 (0.52) | P2RY1ENPP1P2RY12P2RY11P2RX1 | |
| SCHEMBL22399998 | 0.85 | P2RY1 (0.52) | P2RY1ENPP1P2RY12P2RY11P2RX1 | |
| SCHEMBL19465002 | 0.85 | P2RY1 (0.52) | P2RY1ENPP1P2RY12P2RY11P2RX1 | |
| SCHEMBL23098404 | 0.85 | P2RY1 (0.52) | P2RY1ENPP1P2RY12P2RY11P2RX1 | |
| SCHEMBL19464889 | 0.85 | P2RY1 (0.52) | P2RY1ENPP1P2RY12P2RY11P2RX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3445368-B1 | COMPOUNDS AND METHODS FOR TREATING NEUROLOGICAL AND CARDIOVASCULAR CONDITIONS | ASTROCYTE PHARMACEUTICALS INC (US) | 2024-07-17 | — | — | EP | disclosed |