Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 5/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | SSTR1 | P30872 | 1/20 | 0.42 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.42 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.38 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.38 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.38 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.38 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.38 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.38 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.36 |
| ▸ | HTR4 | Q13639 | 4/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | SMYD3 | Q9H7B4 | 2/20 | 0.35 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.34 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19717405 | 0.79 | EPHX1 (0.48) | EPHX1POLBSSTR1SSTR4PDK1 | |
| SCHEMBL6697632 | 0.77 | EPHX1 (0.59) | EPHX1POLBSSTR1SSTR4PDK1 | |
| SCHEMBL15447615 | 0.75 | EPHX1 (0.57) | EPHX1POLBSSTR1SSTR4PDK1 | |
| SCHEMBL9330440 | 0.75 | EPHX1 (0.44) | EPHX1POLBSSTR1SSTR4PDK1 | |
| SCHEMBL12308373 | 0.74 | SSTR4 (0.48) | EPHX1POLBSSTR1SSTR4PDK1 | |
| SCHEMBL3414046 | 0.73 | EPHX1 (0.53) | EPHX1POLBGNAI3GNAO1GNAI1 | |
| SCHEMBL16580725 | 0.72 | EPHX1 (0.48) | EPHX1POLBSSTR1SSTR4GNAI3 | |
| SCHEMBL12334726 | 0.71 | EPHX1 (0.52) | EPHX1POLBSSTR1SSTR4PDK1 | |
| SCHEMBL19717270 | 0.70 | EPHX1 (0.50) | EPHX1POLBSSTR1SSTR4PDK1 | |
| SCHEMBL12308683 | 0.70 | EPHX1 (0.46) | EPHX1POLBSSTR1SSTR4PDK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024145931-A1 | SMALL MOLECULE INHIBITOR FOR β-CATENIN/BCL9 PROTEIN-PROTEIN INTERACTION AND USE THEREOF | 上海医药工业研究院有限公司 | 2024-07-11 | — | — | WO | disclosed |