SCHEMBL29318133

SCHEMBL29318133

COc1ccc(S(=O)(=O)NC(=O)C(C)(C)Oc2cccc(C3CCCN(S(=O)(=O)c4cccc(-c5ccc(C(C)C)cc5)c4)C3)c2)cc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
BCL9 O00512 20/20 1.00
CTNNB1 P35222 20/20 1.00

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29318267 0.95 BCL9 (0.91) BCL9CTNNB1
SCHEMBL29318364 0.94 BCL9 (1.00) BCL9CTNNB1
SCHEMBL29318140 0.94 BCL9 (0.91) BCL9CTNNB1
SCHEMBL29319979 0.93 BCL9 (0.89) BCL9CTNNB1
SCHEMBL29318447 0.92 BCL9 (1.00) BCL9CTNNB1
SCHEMBL29320503 0.92 BCL9 (1.00) BCL9CTNNB1
SCHEMBL29321520 0.92 BCL9 (0.87) BCL9CTNNB1
SCHEMBL29318075 0.92 BCL9 (1.00) BCL9CTNNB1
SCHEMBL29320170 0.92 BCL9 (0.89) BCL9CTNNB1
SCHEMBL29318261 0.91 BCL9 (1.00) BCL9CTNNB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024145931-A1 SMALL MOLECULE INHIBITOR FOR β-CATENIN/BCL9 PROTEIN-PROTEIN INTERACTION AND USE THEREOF 上海医药工业研究院有限公司 2024-07-11 WO disclosed