SCHEMBL29319295

SCHEMBL29319295

CCc1nc2cc(C)ccc2n1-c1ccc(-c2c3ccccc3c(-c3ccc4c(c3)C(C)(C)c3ccccc3-4)c3ccccc23)cc1

nearest known ligand 0.43

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
PDE10A Q9Y233 16/20 0.43
KCNH2 Q12809 1/20 0.40
NLRP3 Q96P20 1/20 0.35
SIRT2 Q8IXJ6 1/20 0.35
SIRT1 Q96EB6 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29319312 0.94 PDE10A (0.37) PDE10AKCNH2NLRP3
SCHEMBL21392676 0.92 KDM4E (0.37) PDE10A
SCHEMBL26343713 0.91 KDM4E (0.37) PDE10A
SCHEMBL29319298 0.87 SIRT2 (0.41) PDE10ANLRP3SIRT2SIRT1
SCHEMBL24674378 0.86 KDM4E (0.35) PDE10A
SCHEMBL24674256 0.86 KDM4E (0.35) PDE10A
SCHEMBL24673795 0.86 KDM4E (0.35) PDE10A
SCHEMBL26343718 0.86 PDE10A (0.36) PDE10A
SCHEMBL26343692 0.85 PDE10A (0.37) PDE10A
SCHEMBL29319234 0.83 PDE10A (0.49) PDE10AKCNH2NLRP3SIRT2SIRT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240244871-A1 ORGANIC LIGHT EMITTING DIODE AND ORGANIC LIGHT EMITTING DEVICE INCLUDING THE SAME LG DISPLAY CO., LTD. (KR) 2024-07-18 US disclosed
US-20240244871-A1 ORGANIC LIGHT EMITTING DIODE AND ORGANIC LIGHT EMITTING DEVICE INCLUDING THE SAME LG DISPLAY CO., LTD. (KR) 2024-07-18 US disclosed
US-20240244970-A1 ORGANIC LIGHT EMITTING DIODE AND ORGANIC LIGHT EMITTING DEVICE INCLUDING THE SAME LG DISPLAY CO., LTD. (KR) 2024-07-18 US disclosed
US-20240244970-A1 ORGANIC LIGHT EMITTING DIODE AND ORGANIC LIGHT EMITTING DEVICE INCLUDING THE SAME LG DISPLAY CO., LTD. (KR) 2024-07-18 US disclosed