⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Pyridine SCHEMBL1063058 | 0.86 | — | — | |
| Pyridine SCHEMBL6014218 | 0.83 | TSHR (0.64) | — | |
| Pyridine SCHEMBL11412722 | 0.83 | TSHR (0.64) | — | |
| Pyridine SCHEMBL3627909 | 0.82 | — | — | |
| Pyridine SCHEMBL28299177 | 0.82 | — | — | |
| Pyridine SCHEMBL1066444 | 0.82 | TSHR (0.75) | — | |
| Pyridine SCHEMBL27737222 | 0.82 | TSHR (0.75) | — | |
| Pyridine SCHEMBL28208929 | 0.82 | — | — | |
| Pyridine SCHEMBL6346183 | 0.82 | TSHR (0.90) | — | |
| Pyridine SCHEMBL28087944 | 0.80 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190151329-A1 | THERAPEUTIC USE OF DIAMINOPHENOTHIAZINES | WISTA LABORATORIES LTD. (SG) | 2019-05-23 | — | — | US | disclosed |
| EP-2954932-A1 | THERAPEUTIC USE OF DIAMINOPHENOTHIAZINES | WisTa Laboratories Ltd. (SG) | 2015-12-16 | — | — | EP | disclosed |
| WO-2015110263-A1 | CARBAZOLE AND CARBOLINE COMPOUNDS FOR USE IN THE DIAGNOSIS, TREATMENT, ALLEVIATION OR PREVENTION OF DISORDERS ASSOCIATED WITH AMYLOID OR AMYOLID-LIKE PROTEINS | AC IMMUNE SA (CH) | 2015-07-30 | — | — | WO | disclosed |
| CN-104744358-A | Pyridine formylhydrazine compounds with insecticidal activity and preparation method and application thereof | UNIV ZHEJIANG TECHNOLOGY | 2015-07-01 | — | — | CN | disclosed |
| EP-2205245-B1 | THERAPEUTIC USE OF DIAMINOPHENOTHIAZINES | WISTA LAB LTD (SG) | 2015-06-24 | — | — | EP | disclosed |
| CN-102712632-A | Inhibitors of flaviviridae viruses | GILEAD SCIENCES INC (US) | 2012-10-03 | — | — | CN | disclosed |
| EP-2013191-B1 | 3,7-DIAMINO-10H-PHENOTHIAZINE SALTS AND THEIR USE | WISTA LAB LTD (SG) | 2010-08-18 | — | — | EP | disclosed |
| EP-2205245-A1 | THERAPEUTIC USE OF DIAMINOPHENOTHIAZINES | Wista Laboratories Ltd. (SG) | 2010-07-14 | — | — | EP | disclosed |
| WO-2009044127-A1 | THERAPEUTIC USE OF DIAMINOPHENOTHIAZINES | WISTA LABORATORIES LTD. (GB) | 2009-04-09 | — | — | WO | disclosed |
| EP-2013191-A2 | 3,7-DIAMINO-10H-PHENOTHIAZINE SALTS AND THEIR USE | Wista Laboratories Ltd. (SG) | 2009-01-14 | — | — | EP | disclosed |
| WO-2007110627-A2 | 3,7-DIAMINO-10H-PHENOTHIAZINE SALTS AND THEIR USE | WISTA LABORATORIES LTD. (SG) | 2007-10-04 | — | — | WO | disclosed |