SCHEMBL29322392

SCHEMBL29322392

O=C1CCC(c2coc3ccc4cc(Br)ccc4c23)C(=O)N1

nearest known ligand 0.41

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
CRBN Q96SW2 15/20 0.41
DDB1 Q16531 14/20 0.41
IDO1 P14902 2/20 0.40
SIRT2 Q8IXJ6 2/20 0.38
SIRT1 Q96EB6 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23634846 0.87 DDB1 (0.47) CRBNDDB1IDO1SIRT2SIRT1
SCHEMBL23634964 0.87 DDB1 (0.47) CRBNDDB1IDO1SIRT2SIRT1
SCHEMBL23634965 0.87 DDB1 (0.47) CRBNDDB1IDO1SIRT2SIRT1
SCHEMBL24950356 0.87 CRBN (0.46) CRBNDDB1
SCHEMBL23634982 0.86 CRBN (0.41) CRBNDDB1
SCHEMBL23634857 0.86 CRBN (0.41) CRBNDDB1
SCHEMBL23634859 0.86 CRBN (0.41) CRBNDDB1
SCHEMBL23634879 0.85 DDB1 (0.40) CRBNDDB1IDO1
SCHEMBL26159211 0.84 DDB1 (0.42) CRBNDDB1
SCHEMBL23634993 0.84 DDB1 (0.51) CRBNDDB1IDO1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4400499-A1 GLUTARIMIDE COMPOUND AND USE THEREOF Medshine Discovery Inc. (CN) 2024-07-17 EP disclosed