Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | GSTO1 | P78417 | 1/20 | 0.46 |
| ▸ | PPARD | Q03181 | 6/20 | 0.45 |
| ▸ | PPARA | Q07869 | 5/20 | 0.44 |
| ▸ | PPARG | P37231 | 3/20 | 0.44 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.41 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | WNT3A | P56704 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2906440 | 0.92 | PPARD (0.50) | ALDH1A1L3MBTL1GSTO1PPARDPPARA | |
| SCHEMBL2900862 | 0.81 | PPARD (0.54) | ALDH1A1L3MBTL1GSTO1PPARDPPARA | |
| SCHEMBL4187098 | 0.79 | PPARD (0.47) | ALDH1A1L3MBTL1GSTO1PPARDPPARA | |
| SCHEMBL2906603 | 0.79 | PPARD (0.48) | ALDH1A1L3MBTL1GSTO1PPARDPPARA | |
| SCHEMBL2908805 | 0.78 | KDM1A (0.56) | ALDH1A1PPARDMEN1KMT2AUSP2 | |
| SCHEMBL2901181 | 0.78 | PPARD (0.47) | ALDH1A1L3MBTL1GSTO1PPARDPPARA | |
| SCHEMBL2900976 | 0.78 | PPARD (0.47) | ALDH1A1L3MBTL1GSTO1PPARDPPARA | |
| SCHEMBL2903594 | 0.76 | PPARD (0.49) | ALDH1A1L3MBTL1GSTO1PPARDPPARA | |
| SCHEMBL2903604 | 0.75 | PPARD (0.45) | ALDH1A1L3MBTL1GSTO1PPARDPPARA | |
| SCHEMBL2906629 | 0.75 | PPARD (0.48) | ALDH1A1L3MBTL1GSTO1PPARDPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1951692-B1 | OXAZOLE AND THIAZOLE PPAR MODULATOR | IRM LLC (BM) | 2010-08-18 | — | — | EP | disclosed |
| US-20100048453-A1 | OXAZOLE AND THIAZOLE PPAR MODULATOR | IRM LLC (BM) | 2010-02-25 | — | — | US | disclosed |
| US-20100048453-A1 | OXAZOLE AND THIAZOLE PPAR MODULATOR | IRM LLC (BM) | 2010-02-25 | — | — | US | disclosed |
| US-20100048453-A1 | OXAZOLE AND THIAZOLE PPAR MODULATOR | IRM LLC (BM) | 2010-02-25 | — | — | US | disclosed |
| EP-1951692-A1 | OXAZOLE AND THIAZOLE PPAR MODULATOR | IRM LLC (BM) | 2008-08-06 | — | — | EP | disclosed |
| WO-2007056496-A1 | OXAZOLE AND THIAZOLE PPAR MODULATOR | IRM LLC (BM) | 2007-05-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100048453-A1 | OXAZOLE AND THIAZOLE PPAR MODULATOR | PPARD, PPARG, PPARA | ALDH1A1 815/4885L3MBTL1 4013/4885GSTO1 573/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.