Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AAK1 | Q2M2I8 | 4/20 | 0.46 |
| ▸ | ATR | Q13535 | 1/20 | 0.42 |
| ▸ | METAP1 | P53582 | 1/20 | 0.38 |
| ▸ | LCK | P06239 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | RORC | P51449 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.34 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.34 |
| ▸ | GSK3B | P49841 | 1/20 | 0.34 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.34 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12358958 | 0.88 | AAK1 (0.44) | AAK1ATRMETAP1LCKSMN1; SMN2 | |
| SCHEMBL4900478 | 0.87 | AAK1 (0.47) | AAK1ATRMETAP1LCKMAPK1 | |
| SCHEMBL24070144 | 0.87 | AAK1 (0.47) | AAK1LCKSMN1; SMN2KDM4ECYP1A2 | |
| SCHEMBL23500611 | 0.84 | ATR (0.42) | AAK1ATRMETAP1RORCLMNA | |
| SCHEMBL21339691 | 0.84 | ATR (0.42) | ATRMETAP1LCKMAPK1KDM4E | |
| SCHEMBL30307813 | 0.83 | KDM4E (0.46) | MAPK1SMN1; SMN2KDM4ELMNANPC1 | |
| SCHEMBL20502298 | 0.83 | KDM4E (0.46) | MAPK1SMN1; SMN2KDM4ELMNANPC1 | |
| SCHEMBL21500091 | 0.82 | AAK1 (0.49) | AAK1ATRMETAP1LCKSMN1; SMN2 | |
| SCHEMBL29527107 | 0.82 | AAK1 (0.49) | AAK1ATRMETAP1LCKSMN1; SMN2 | |
| SCHEMBL30673292 | 0.82 | AAK1 (0.46) | AAK1ATRMETAP1LCKSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024148274-A1 | COMPLEMENT INHIBITION | APELLIS PHARMACEUTICALS, INC. (US) | 2024-07-11 | — | — | WO | disclosed |