SCHEMBL29324431

SCHEMBL29324431

CCCC1CC=C(c2ccc(OCC3CCCC3)c(F)c2F)CC1

nearest known ligand 0.35

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
PTGDR2 Q9Y5Y4 3/20 0.31
ALOX5AP P20292 1/20 0.31
FEN1 P39748 1/20 0.31
PTGER1 P34995 2/20 0.31
BRD4 O60885 1/20 0.30
SLC6A4 P31645 1/20 0.30
HTR6 P50406 1/20 0.30
CCNT1 O60563 2/20 0.30
CDK9 P50750 2/20 0.30
C5AR1 P21730 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29324453 0.92 CYP1A2 (0.30)
SCHEMBL29324418 0.91 CCNT1 (0.32) PTGDR2ALOX5APFEN1BRD4SLC6A4
SCHEMBL13378230 0.89 NPC1 (0.34) CCNT1CDK9
SCHEMBL31722819 0.89 NPC1 (0.34) CCNT1CDK9
SCHEMBL21655186 0.88
SCHEMBL9405850 0.86 NPC1 (0.32) CCNT1CDK9
SCHEMBL9406030 0.86 NPC1 (0.32) CCNT1CDK9
SCHEMBL8938724 0.85 ESR2 (0.36) CCNT1CDK9
SCHEMBL29324369 0.85 NPY1R (0.35)
SCHEMBL26805173 0.85 MCHR1 (0.33) ALOX5APFEN1SLC6A4HTR6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4400561-A1 LIQUID-CRYSTAL MEDIUM Merck Patent GmbH (DE) 2024-07-17 EP disclosed