Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IP6K1 | Q92551 | 1/20 | 0.42 |
| ▸ | LRRK2 | Q5S007 | 3/20 | 0.42 |
| ▸ | ELANE | P08246 | 2/20 | 0.41 |
| ▸ | ALOX5AP | P20292 | 3/20 | 0.40 |
| ▸ | FEN1 | P39748 | 3/20 | 0.40 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.39 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.39 |
| ▸ | XDH | P47989 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | JAK3 | P52333 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16464454 | 0.98 | IP6K1 (0.43) | IP6K1LRRK2ELANEALOX5APFEN1 | |
| SCHEMBL16054252 | 0.95 | IP6K1 (0.43) | IP6K1LRRK2ELANEALOX5APFEN1 | |
| SCHEMBL29846953 | 0.92 | IP6K1 (0.44) | IP6K1ELANEALOX5APFEN1SSTR4 | |
| SCHEMBL23761282 | 0.92 | IP6K1 (0.44) | IP6K1ELANEALOX5APFEN1SSTR4 | |
| SCHEMBL21606914 | 0.85 | NMT1 (0.44) | IP6K1KCNH2 | |
| SCHEMBL23417584 | 0.85 | ALOX5AP (0.45) | IP6K1ALOX5APFEN1SSTR4KCNH2 | |
| Hydrochloric Acid SCHEMBL30785461 | 0.84 | NMT1 (0.43) | IP6K1KCNH2 | |
| Hydrochloric Acid SCHEMBL23167968 | 0.84 | ALOX5AP (0.44) | IP6K1ALOX5APFEN1SSTR4KCNH2 | |
| Hydrochloric Acid SCHEMBL27158179 | 0.84 | NMT1 (0.43) | IP6K1KCNH2 | |
| SCHEMBL27303201 | 0.84 | IP6K1 (0.41) | IP6K1ELANEALOX5APFEN1SSTR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240239797-A1 | AKT1 MODULATORS | ALTEROME THERAPEUTICS, INC. | 2024-07-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240239797-A1 | AKT1 MODULATORS | AKT1S1, AKT1, AKT2 | IP6K1 117/4885LRRK2 103/4885ELANE 4199/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.