SCHEMBL29324609

SCHEMBL29324609

COC(=O)c1ccc(C2CN(CC(F)F)CCN2Cc2c(OC)cc(C)c3c2ccn3C(=O)OC(C)(C)C)cc1N

nearest known ligand 0.40

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
CFB P00751 20/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31056606 1.00 CFB (0.40) CFB
SCHEMBL29324673 1.00 CFB (0.40) CFB
SCHEMBL29321489 0.94 CFB (0.44) CFB
SCHEMBL31056573 0.94 CFB (0.44) CFB
SCHEMBL31056552 0.93 CFB (0.40) CFB
SCHEMBL29320914 0.93 CFB (0.40) CFB
SCHEMBL31056832 0.92 CFB (0.40) CFB
SCHEMBL31056920 0.92 CFB (0.40) CFB
SCHEMBL31056526 0.92 CFB (0.40) CFB
SCHEMBL29324239 0.92 CFB (0.40) CFB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024148274-A1 COMPLEMENT INHIBITION APELLIS PHARMACEUTICALS, INC. (US) 2024-07-11 WO disclosed