Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNP | P00491 | 11/20 | 0.42 |
| ▸ | MTAP | Q13126 | 6/20 | 0.35 |
| ▸ | AHCY | P23526 | 2/20 | 0.34 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.34 |
| ▸ | SLC5A1 | P13866 | 1/20 | 0.34 |
| ▸ | SLC5A2 | P31639 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29323411 | 1.00 | PNP (0.42) | PNPMTAPAHCYADORA2BSLC5A1 | |
| SCHEMBL19367427 | 1.00 | PNP (0.42) | PNPMTAPAHCYADORA2BSLC5A1 | |
| SCHEMBL29325515 | 1.00 | PNP (0.42) | PNPMTAPAHCYADORA2BSLC5A1 | |
| SCHEMBL17175066 | 1.00 | PNP (0.42) | PNPMTAPAHCYADORA2BSLC5A1 | |
| SCHEMBL29325510 | 0.86 | PNP (0.58) | PNPMTAPAHCYADORA2B | |
| SCHEMBL16883369 | 0.86 | PNP (0.41) | PNPMTAPAHCYADORA2B | |
| SCHEMBL26348051 | 0.86 | PNP (0.58) | PNPMTAPAHCYADORA2B | |
| SCHEMBL17175063 | 0.86 | PNP (0.58) | PNPMTAPAHCYADORA2B | |
| SCHEMBL29325512 | 0.86 | PNP (0.58) | PNPMTAPAHCYADORA2B | |
| SCHEMBL29323408 | 0.86 | PNP (0.58) | PNPMTAPAHCYADORA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240238323-A1 | MODIFIED NUCLEOSIDES AND NUCLEOTIDES ANALOGS AS ANTIVIRAL AGENTS FOR CORONA AND OTHER VIRUSES | EMORY UNIVERSITY | 2024-07-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240238323-A1 | MODIFIED NUCLEOSIDES AND NUCLEOTIDES ANALOGS AS ANTIVIRAL AGENTS FOR CORONA AND OTHER VIRUSES | MTAP, PNP, SARS1 | PNP 2/4885MTAP 1/4885AHCY 804/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.