Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC2A1 | P11166 | 1/20 | 0.47 |
| ▸ | CYP46A1 | Q9Y6A2 | 1/20 | 0.45 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.44 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | PIM2 | Q9P1W9 | 2/20 | 0.43 |
| ▸ | PIM1 | P11309 | 1/20 | 0.43 |
| ▸ | PORCN | Q9H237 | 1/20 | 0.43 |
| ▸ | AXL | P30530 | 2/20 | 0.43 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.43 |
| ▸ | WNT3A | P56704 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | ABL1 | P00519 | 2/20 | 0.42 |
| ▸ | DHODH | Q02127 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31056485 | 1.00 | SLC2A1 (0.47) | SLC2A1CYP46A1MKNK1MKNK2KDM4E | |
| SCHEMBL29320335 | 0.86 | CA12 (0.50) | CYP46A1MKNK1MKNK2KDM4EALDH1A1 | |
| SCHEMBL27272854 | 0.85 | ABL1 (0.44) | KDM4EALDH1A1GLAGAAPIM2 | |
| SCHEMBL30987732 | 0.85 | ABL1 (0.44) | KDM4EALDH1A1GLAGAAPIM2 | |
| SCHEMBL29321962 | 0.85 | MKNK1 (0.49) | CYP46A1MKNK1MKNK2KDM4EALDH1A1 | |
| SCHEMBL7821127 | 0.84 | SLC2A1 (0.68) | SLC2A1CYP46A1KDM4EALDH1A1GAA | |
| SCHEMBL27272872 | 0.82 | ABL1 (0.44) | CYP46A1KDM4EALDH1A1GLAGAA | |
| SCHEMBL30987703 | 0.82 | ABL1 (0.44) | CYP46A1KDM4EALDH1A1GLAGAA | |
| SCHEMBL30930680 | 0.82 | AXL (0.58) | KDM4EAXLHSD17B10ABL1DHODH | |
| SCHEMBL27284549 | 0.82 | AXL (0.58) | KDM4EAXLHSD17B10ABL1DHODH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024148274-A1 | COMPLEMENT INHIBITION | APELLIS PHARMACEUTICALS, INC. (US) | 2024-07-11 | — | — | WO | disclosed |
| WO-2024148274-A1 | COMPLEMENT INHIBITION | APELLIS PHARMACEUTICALS, INC. (US) | 2024-07-11 | — | — | WO | disclosed |