Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCQ | Q04759 | 20/20 | 0.57 |
| ▸ | PRKCD | Q05655 | 16/20 | 0.57 |
| ▸ | PRKCH | P24723 | 2/20 | 0.45 |
| ▸ | PRKCE | Q02156 | 2/20 | 0.45 |
| ▸ | PRKCB | P05771 | 1/20 | 0.45 |
| ▸ | LCK | P06239 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1146400 | 0.86 | PRKCQ (0.60) | PRKCQPRKCD | |
| SCHEMBL1146085 | 0.86 | PRKCQ (0.57) | PRKCQPRKCDPRKCHPRKCEPRKCB | |
| SCHEMBL2935616 | 0.81 | PRKCQ (0.59) | PRKCQPRKCDPRKCHPRKCE | |
| SCHEMBL2936236 | 0.81 | PRKCQ (0.59) | PRKCQPRKCDPRKCHPRKCE | |
| SCHEMBL1145662 | 0.79 | PRKCQ (0.74) | PRKCQPRKCDPRKCHPRKCE | |
| SCHEMBL1146127 | 0.77 | PRKCQ (0.61) | PRKCQPRKCDPRKCHPRKCEPRKCB | |
| SCHEMBL1146327 | 0.77 | PRKCQ (0.57) | PRKCQPRKCDPRKCHPRKCEPRKCB | |
| SCHEMBL5518130 | 0.76 | PRKCQ (0.67) | PRKCQPRKCDPRKCHPRKCEPRKCB | |
| SCHEMBL1146269 | 0.76 | PRKCQ (0.54) | PRKCQPRKCDPRKCHPRKCE | |
| SCHEMBL4447124 | 0.75 | SRC (0.71) | PRKCQPRKCD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2229377-A1 | 5-ALKYL/ALKENYL-3-CYANOPYRIDINES AS KINASE INHIBITORS | Wyeth LLC (US) | 2010-09-22 | — | — | EP | disclosed |
| WO-2009076602-A1 | 5-ALKYL/ALKENYL-3-CYANOPYRIDINES AS KINASE INHIBITORS | WYETH (US) | 2009-06-18 | — | — | WO | disclosed |