Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SYK | P43405 | 2/20 | 0.39 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | KDR | P35968 | 9/20 | 0.37 |
| ▸ | MET | P08581 | 1/20 | 0.35 |
| ▸ | PRKCQ | Q04759 | 2/20 | 0.35 |
| ▸ | BRAF | P15056 | 5/20 | 0.35 |
| ▸ | ESR1 | P03372 | 2/20 | 0.34 |
| ▸ | ABL1 | P00519 | 1/20 | 0.34 |
| ▸ | BCR | P11274 | 1/20 | 0.34 |
| ▸ | CDK1 | P06493 | 1/20 | 0.34 |
| ▸ | ULK1 | O75385 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29329538 | 0.93 | SYK (0.39) | SYKKCNH2KDRMETPRKCQ | |
| SCHEMBL29329364 | 0.90 | KDR (0.39) | SYKKDRPRKCQBRAFESR1 | |
| SCHEMBL29330254 | 0.89 | SYK (0.42) | SYKMETPRKCQESR1 | |
| SCHEMBL29330032 | 0.88 | SYK (0.42) | SYKMETPRKCQESR1ABL1 | |
| SCHEMBL29329126 | 0.87 | SYK (0.40) | SYKMETPRKCQESR1ABL1 | |
| SCHEMBL24539421 | 0.86 | SYK (0.41) | SYKCHRNA7KCNH2PRKCQESR1 | |
| SCHEMBL29330248 | 0.86 | ESR1 (0.46) | SYKCHRNA7KCNH2KDRPRKCQ | |
| SCHEMBL29746074 | 0.86 | SYK (0.41) | SYKCHRNA7KCNH2PRKCQESR1 | |
| SCHEMBL29330251 | 0.85 | SYK (0.41) | SYKMETPRKCQESR1ABL1 | |
| SCHEMBL29330255 | 0.85 | ESR1 (0.42) | SYKKCNH2METPRKCQESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024151919-A1 | COMPOUNDS AND COMPOSITIONS FOR TREATING CONDITIONS ASSOCIATED WITH STING ACTIVITY | IFM DUE, INC. (US) | 2024-07-18 | — | — | WO | disclosed |