Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.53 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.53 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 4/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 4/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | JMJD6 | Q6NYC1 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19975594 | 0.85 | KMT2A (0.50) | KMT2ATDP1SLC6A2SLC6A3LMNA | |
| SCHEMBL24993710 | 0.80 | TDP1 (0.62) | KMT2ATDP1SLC6A2SLC6A3LMNA | |
| SCHEMBL29329010 | 0.80 | TDP1 (0.43) | KMT2ATDP1SLC6A2SLC6A3LMNA | |
| SCHEMBL25187553 | 0.78 | TDP1 (0.51) | KMT2ATDP1SLC6A2SLC6A3LMNA | |
| SCHEMBL19975598 | 0.77 | KMT2A (0.45) | KMT2ATDP1SLC6A2SLC6A3LMNA | |
| SCHEMBL24359759 | 0.76 | TDP1 (0.45) | KMT2ATDP1SLC6A2SLC6A3LMNA | |
| SCHEMBL6282770 | 0.76 | KMT2A (0.81) | KMT2ATDP1SLC6A2SLC6A3LMNA | |
| SCHEMBL25713483 | 0.76 | TDP1 (0.64) | KMT2ATDP1SLC6A2SLC6A3LMNA | |
| SCHEMBL20830625 | 0.75 | TDP1 (0.67) | KMT2ATDP1SLC6A2SLC6A3LMNA | |
| SCHEMBL13469247 | 0.74 | TDP1 (0.71) | KMT2ATDP1SLC6A2SLC6A3LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12043833-B2 | Targeted compositions | ARBUTUS BIOPHARMA CORPORATION (CA) | 2024-07-23 | — | — | US | disclosed |