Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.58 |
| ▸ | TSHR | P16473 | 3/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.58 |
| ▸ | GAA | P10253 | 1/20 | 0.58 |
| ▸ | RAB9A | P51151 | 1/20 | 0.58 |
| ▸ | PKM | P14618 | 3/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | TTR | P02766 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.46 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.46 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.46 |
| ▸ | HTR1A | P08908 | 1/20 | 0.46 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.46 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8830887 | 0.90 | KDM4E (0.63) | KDM4ETSHRALDH1A1GAARAB9A | |
| SCHEMBL16260620 | 0.81 | CA12 (0.62) | TSHRRAB9APKMHPGDHTT | |
| SCHEMBL6915145 | 0.80 | TPMT (0.56) | KDM4ETSHRALDH1A1PKMHPGD | |
| SCHEMBL349293 | 0.79 | KDM4E (0.50) | KDM4ETSHRALDH1A1GAARAB9A | |
| SCHEMBL31229876 | 0.79 | MAPT (0.49) | KDM4ETSHRALDH1A1GAARAB9A | |
| SCHEMBL2048079 | 0.79 | MAPT (0.49) | KDM4ETSHRALDH1A1GAARAB9A | |
| 3,4,5-Triacetoxybenzoic Acid SCHEMBL716891 | 0.79 | KDM4E (0.63) | KDM4ETSHRALDH1A1GAARAB9A | |
| SCHEMBL6970527 | 0.78 | TSHR (0.73) | KDM4ETSHRALDH1A1GAARAB9A | |
| SCHEMBL1923388 | 0.78 | TSHR (0.73) | KDM4ETSHRALDH1A1GAARAB9A | |
| SCHEMBL1572119 | 0.77 | TPMT (0.59) | KDM4ETSHRALDH1A1PKMHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12043833-B2 | Targeted compositions | ARBUTUS BIOPHARMA CORPORATION (CA) | 2024-07-23 | — | — | US | disclosed |