Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3201323 | 0.89 | PTPN1 (0.54) | PTPN1PTPN2 | |
| SCHEMBL2932947 | 0.86 | PTPN1 (0.50) | PTPN1PTPN2 | |
| SCHEMBL3209582 | 0.86 | PTPN1 (0.44) | PTPN1PTPN2 | |
| SCHEMBL3209574 | 0.78 | PTPN1 (0.56) | PTPN1PTPN2 | |
| SCHEMBL2935888 | 0.77 | PTPN1 (0.59) | PTPN1PTPN2 | |
| SCHEMBL2935889 | 0.75 | PTPN1 (0.43) | PTPN1PTPN2 | |
| SCHEMBL3919036 | 0.75 | PTPN1 (0.56) | PTPN1PTPN2 | |
| SCHEMBL3923934 | 0.74 | PTPN1 (0.53) | PTPN1PTPN2 | |
| SCHEMBL2934872 | 0.74 | PTPN1 (0.53) | PTPN1PTPN2 | |
| SCHEMBL2934233 | 0.73 | PTPN1 (0.48) | PTPN1PTPN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2227245-A2 | COMBINATION OF PROTEIN TYROSINE PHOSPHATASE INHIBITORS AND HUMAN GROWTH HORMONE FOR THE TREATMENT OF MUSCLE ATROPHY AND RELATED DISORDERS | Novartis AG (CH) | 2010-09-15 | — | — | EP | disclosed |
| WO-2009068689-A2 | COMBINATION OF PROTEIN TYROSINE PHOSPHATASE INHIBITORS AND HUMAN GROWTH HORMONE FOR THE TREATMENT OF MUSCLE ATROPHY AND RELATED DISORDERS | NOVARTIS AG (CH) | 2009-06-04 | — | — | WO | disclosed |