Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 14/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | CHEK1 | O14757 | 2/20 | 0.35 |
| ▸ | CNR1 | P21554 | 1/20 | 0.34 |
| ▸ | CNR2 | P34972 | 1/20 | 0.34 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.34 |
| ▸ | P2RX2 | Q9UBL9 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1928236 | 0.76 | HRH3 (0.37) | HRH3CNR1CNR2P2RX3P2RX2 | |
| SCHEMBL1928559 | 0.76 | HRH3 (0.39) | HRH3KMT2AMEN1CHEK1 | |
| SCHEMBL1929020 | 0.75 | MAPT (0.44) | HRH3KMT2AMEN1CHEK1 | |
| SCHEMBL1928320 | 0.73 | HRH3 (0.44) | HRH3CHEK1 | |
| SCHEMBL1928840 | 0.73 | SCD (0.48) | HRH3CNR1CNR2 | |
| SCHEMBL1928720 | 0.71 | SLC6A4 (0.43) | HRH3CNR1CNR2 | |
| SCHEMBL1927682 | 0.71 | SCD (0.47) | HRH3 | |
| SCHEMBL1926949 | 0.70 | HRH3 (0.43) | HRH3 | |
| SCHEMBL1926962 | 0.69 | HRH3 (0.45) | HRH3CNR1CNR2 | |
| SCHEMBL12311932 | 0.68 | HRH3 (0.49) | HRH3CHEK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1421074-B1 | NOVEL COMPOUNDS | ASTRAZENECA AB (SE) | 2010-09-29 | — | — | EP | disclosed |