Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.55 |
| ▸ | NPC1 | O15118 | 2/20 | 0.54 |
| ▸ | RAB9A | P51151 | 2/20 | 0.54 |
| ▸ | BCL9 | O00512 | 6/20 | 0.50 |
| ▸ | CTNNB1 | P35222 | 6/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.50 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.49 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.49 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.49 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.47 |
| ▸ | JAK2 | O60674 | 2/20 | 0.47 |
| ▸ | JAK1 | P23458 | 2/20 | 0.47 |
| ▸ | TYK2 | P29597 | 2/20 | 0.47 |
| ▸ | JAK3 | P52333 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12904501 | 0.91 | SMN1; SMN2 (0.56) | SMN1; SMN2CYP2C19NPC1RAB9ABCL9 | |
| SCHEMBL29333108 | 0.91 | SMN1; SMN2 (0.53) | SMN1; SMN2CYP2C19NPC1RAB9ABCL9 | |
| SCHEMBL29333167 | 0.90 | SMN1; SMN2 (0.52) | SMN1; SMN2CYP2C19NPC1RAB9ABCL9 | |
| SCHEMBL29332909 | 0.90 | SMN1; SMN2 (0.52) | SMN1; SMN2CYP2C19NPC1RAB9ABCL9 | |
| SCHEMBL29332910 | 0.90 | SMN1; SMN2 (0.52) | SMN1; SMN2CYP2C19NPC1RAB9ABCL9 | |
| SCHEMBL30994695 | 0.90 | SMN1; SMN2 (0.52) | SMN1; SMN2CYP2C19NPC1RAB9ABCL9 | |
| SCHEMBL30994598 | 0.90 | SMN1; SMN2 (0.52) | SMN1; SMN2CYP2C19NPC1RAB9ABCL9 | |
| SCHEMBL30994568 | 0.90 | SMN1; SMN2 (0.52) | SMN1; SMN2CYP2C19NPC1RAB9ABCL9 | |
| SCHEMBL29332951 | 0.90 | SMN1; SMN2 (0.52) | SMN1; SMN2CYP2C19NPC1RAB9ABCL9 | |
| SCHEMBL29332940 | 0.90 | SMN1; SMN2 (0.52) | SMN1; SMN2CYP2C19NPC1RAB9ABCL9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024149728-A1 | SUBSTITUTED (HETERO)ANILINES AND THEIR USE | ASTRAZENECA AB (SE) | 2024-07-18 | — | — | WO | disclosed |